Overweight and the Metabolic Syndrome

From Bench to Bedside

  • George A. Bray
  • Donna H. Ryan

Part of the Endocrine Updates book series (ENDO, volume 26)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Andrew A. Butler, James L. Trevaskis, Christopher D. Morrison
    Pages 1-21
  3. Wm. Cameron Chumlea
    Pages 23-35
  4. Ali H. Mokdad, Earl S. Ford
    Pages 37-53
  5. Raul A. Bastarrachea, Jack W. Kent Jr., Jeff T. Williams, Guowen Cai, Shelley A. Cole, Anthony G. Comuzzie
    Pages 55-81
  6. Barry E. Levin, Deborah J. Clegg
    Pages 83-103
  7. Tamara Tchkonia, Barbara E. Corkey, James L. Kirkland
    Pages 105-123
  8. Frederico G. S. Toledo, David E. Kelley
    Pages 125-136
  9. Jean-Pierre Després, Isabelle Lemieux, Natalie Alméras
    Pages 137-152
  10. Sonia Caprio, Ram Weiss
    Pages 153-168
  11. George A. Bray, Donna H. Ryan
    Pages 169-186
  12. Angela P. Makris, Gary D. Foster
    Pages 187-210
  13. John M. Jakicic, Amy D. Otto
    Pages 211-218
  14. Donald A. Williamson, Corby K. Martin, Tiffany M. Stewart
    Pages 219-232
  15. Shiriki K. Kumanyika, Stephen R. Daniels
    Pages 233-253
  16. George A. Bray
    Pages 307-327
  17. Back Matter
    Pages 329-335

About this book


This volume examines the problem of the overweight individual and the metabolic syndrome from the laboratory bench to the bedside. Clearly, translating the findings we make in the laboratory to the betterment of humankind is an important mission. Areas where basic science is making important contributions to the problems associated with metabolic syndrome are illustrated in the chapters on Neuroendocrine Control of Food Intake, Current Views of the Fat Cell as an Endocrine Cell: Lipotoxicity, and Ectopic Fat and Metabolic Syndrome. For each of these, the fast-moving basic science area is opening new vistas for translation to the bedside and clinic.


The larger segment of the book deals with the clinical context for the metabolic syndrome, central adiposity and overweight. The methods for measurement are well described and the application of these methods to evaluating patients and determining the prevalence in society is indicated. Genetic components of overweight and the metabolic syndrome are reviewed. The key role of visceral fat is emphasized by giving it a chapter of its own written by one of the foremost investigators of this problem. The importance of overweight and the metabolic syndrome in children is recognized in a separate chapter.

There are a number of chapters focusing on treatment including behavioral therapy, exercise, diet, medications and surgery. In summary, this book is the alpha and omega of the overweight and metabolic syndrome problem.


Series editor comments:

Drs. Bray and Ryan have assembled a superb panel of authors who bring their expertise to this very timely book for medical practice. The epidemic of obesity is addressed in authoritative and cutting edge chapters ranging from the fundamental genetics and physiology of appetite control through the latest pharmacologic applications and surgical interventions. This is a "must have" volume for those treating patients with appetite disorders, obesity and diabetes, as well as those studying the intrinsic cellular and whole body pathogenesis of this modern population disorder.

Shlomo Melmed, M.D.
Series Editor
Endocrine Updates


body composition endothelium genetics insulin insulin resistance prevention surgery

Editors and affiliations

  • George A. Bray
    • 1
  • Donna H. Ryan
    • 1
  1. 1.Pennington Biomedical Research CenterLouisiana State UniversityBaton RougeUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2006
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-0-387-32163-9
  • Online ISBN 978-0-387-32164-6
  • Series Print ISSN 1566-0729
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology