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Design of Organic Solids

  • Edwin Weber
  • Y. Aoyama
  • M. R. Caira
  • G. R. Desiraju
  • J. P. Glusker
  • A. D. Hamilton
  • R. E. Meléndez
  • A. Nangia

Part of the Topics in Current Chemistry book series (TOPCURRCHEM, volume 198)

Table of contents

  1. Front Matter
    Pages I-IX
  2. Nangia Ashwini, Desiraju Gautam R.
    Pages 57-95
  3. Meléndez Rosa E., Hamilton Andrew D.
    Pages 97-129
  4. Aoyama Yasuhiro
    Pages 131-161
  5. Caira Mino R.
    Pages 163-208
  6. Back Matter
    Pages 209-220

About this book

Introduction

Considering the high level of our knowledge concerning covalent bond formation in the organic chemistry of molecules, our understanding of the principles involved in organic solid design is almost in its infancy. While chemists today are able to synthesize organic molecules of very high complexity using sophisticated methods of preparation, they lack general approaches enabling them to reliably predict organic crystalline or solid structures from molecular descriptors - no matter how simple they are. On the other hand, nearly all the organic matter surrounding us is not in the single-molecule state but aggregated and condensed to form liquid or solid molecular assemblages and structural arrays giving rise to the appearances and properties of organic compounds we usually observe. Obviously, the electrical, optical or magnetic properties of solid organic materials that are important requirements for future technologies and high-tech applications, as well as the stability and solubility behavior of a medicament depend on the structure of the molecule and the intramolecular forces, but even more decisively on the intermolecular forces, i. e. the packing structure of the molecules to which a general approach is lacking. This situation concerned ]. Maddox some years ago to such a degree that he described it as "one of the continuing scandals in the physical sciences" [see (1998) Nature 335:201; see also Ball, P. (1996) Nature 381:648]. The problem of predicting organic solid and crystal structures is very dif- cult.

Keywords

Festkörperchemie Kristallchemie Materialwissenschaft Molekularerkennung Nanostrukture carbon rich compounds crystall engineering kohlenstoffreiche Verbindungen materials science microporous materilas mikroporiger Werkstoff molecular recognition

Editors and affiliations

  • Edwin Weber
    • 1
  • Y. Aoyama
  • M. R. Caira
  • G. R. Desiraju
  • J. P. Glusker
  • A. D. Hamilton
  • R. E. Meléndez
  • A. Nangia
  1. 1.Institut für Organische ChemieTechnische Universität Bergakademie FreibergFreiberg/SachsenGermany

Bibliographic information

  • DOI https://doi.org/10.1007/3-540-69178-2
  • Copyright Information Springer-Verlag Berlin Heidelberg 1998
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-64645-7
  • Online ISBN 978-3-540-69178-5
  • Series Print ISSN 0340-1022
  • Buy this book on publisher's site
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