Table of contents

  1. Front Matter
    Pages I-VIII
  2. S. Akira
    Pages 1-16
  3. R. M. Steinman, H. Hemmi
    Pages 17-58
  4. L. J. McHeyzer-Williams, L. P. Malherbe, M. G. McHeyzer-Williams
    Pages 59-83
  5. J. T. Tan, C. D. Surh
    Pages 85-115
  6. R. M. Welsh, S. K. Kim, M. Cornberg, S. C. Clute, L. K. Selin, Y. N. Naumov
    Pages 117-153
  7. Back Matter
    Pages 179-184

About this book


The ability to remember an antigenic encounter for several decades, even for a life time, is one of the fundamental properties of the immune system. This phenomenon known as "immunological memory", is the foundation upon which the concept if vaccination rests. Therefore, understanding the mechanisms by which immunological memory is regulated is of paramount importance. Recent advances in immunology, particularly in the field of innate immunity, suggest that the innate immune system plays fundamental roles in influencing immunological memory. Indeed, emerging evidence suggests that events that occur early, within hours if not minutes of pathogen or vaccine entry profoundly shape the quantity, quality and duration of immunological memory. The present volume assembles a collection of essays from leading experts that span the entire spectrum research from understanding the molecular mechanisms of innate immune recognition, to dendritic cell function, to the generation and maintenance of antigen-specific B and T-cell responses.


Antigen B cell memory T cell T cell memory Toll-like receptors cell dendritic cells immune system immunology infectious disease innate immunity vaccination vaccine virus

Editors and affiliations

  • Bali Pulendran
    • 1
  • Rafi Ahmed
    • 1
  1. 1.Emory Vaccine CenterAtlanteUSA

Bibliographic information

Industry Sectors
Health & Hospitals