© 2006

Mechanics of Biological Tissue

  • Gerhard A. Holzapfel
  • Ray W. Ogden

Table of contents

  1. Front Matter
    Pages I-XII
  2. Tissue Growth and Remodelling

    1. Front Matter
      Pages 1-1
    2. E. M. Arruda, S. C. Calve, K. Garikipati, K. Grosh, H. Narayanan
      Pages 63-75
    3. E. Kuhl, A. Menzel, K. Garikipati, E. M. Arruda, K. Grosh
      Pages 77-89
    4. M. Doblaré, J. M. García-Aznar, M. J. Gómez-Benito
      Pages 105-118
  3. Micromechanics, Cells and Matrix

    1. Front Matter
      Pages 135-135
    2. F. Boschetti, M.T. Raimondi, F. Migliavacca, M. Cioffi, R. Pietrabissa
      Pages 153-164
    3. H. J. Qi, B. J. F. Bruet, J. S. Palmer, C. Ortiz, M. C. Boyce
      Pages 189-203
  4. Arteries in Health and Disease

    1. Front Matter
      Pages 205-205
    2. P. D. Richardson
      Pages 207-223
    3. G. A. Holzapfel, M. Stadler, Th. C. Gasser
      Pages 225-240

About this book


The mechanics of biological tissues is a multidisciplinary and rapidly expanding area of research. This book highlights some important research directions that combine mechanical sciences with exciting new developments in biology.


It includes state-of-the-art articles on:

  • Tissue growth and remodelling – general continuum theories of growth, remodelling and adaptation, with specific applications to arterial, tendon and cartilage growth and to bone healing.
  • Micromechanics, cells and matrix – measurements of the mechanical properties of cells, engineering of cell systems, constitutive and computational modelling of cells and cell-substrate interactions, and the transition from microscopic modelling to its macroscopic consequences.
  • Arteries in health and disease – analysis of residual stress and its development, modelling the constitutive properties of arterial walls, computational analysis of the effect of stenting on the arterial wall, studies of collagen fibre distributions in saccular aneurysms and the interaction between blood flow and aneurysm development.
  • Biological tissues – the musculo-skeletal system, heart valves, ligaments, intervertebral discs, the uterus and vocal fold tissues, with experimental, modelling and computational perspectives.
  • Image-based analysis – illustration of imaging techniques that have great potential for the analysis of tissue properties and pathologies and for guiding the design of engineered tissue constructs.


This collection of papers should be of interest to theoretical, computational and experimental researchers and doctoral students in the area of biomechanics and in related areas of engineering, biology and medicine.


Biomechanics Biomedical Engineering Growth and Remodeling Mechanobiology Simulation Tissue Engineering Tissue Mechanics bone calculus cartilage mechanics model modeling smooth muscle tissue

Editors and affiliations

  • Gerhard A. Holzapfel
    • 1
  • Ray W. Ogden
    • 2
  1. 1.Institute for Structural Analysis, Computational BiomechanicsGraz University of TechnologyGrazAustria
  2. 2.Department of Mathematics, University GardensUniversity of GlasgowGlasgowUK

Bibliographic information

Industry Sectors
Materials & Steel
Consumer Packaged Goods
Energy, Utilities & Environment
Oil, Gas & Geosciences