Reoviruses: Entry, Assembly and Morphogenesis

  • Polly Roy

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 309)

Table of contents

  1. Front Matter
    Pages I-XVII
  2. K. M. Guglielmi, E. M. Johnson, T. Stehle, T. S. Dermody
    Pages 1-38
  3. S. Lopez, C. F. Arias
    Pages 39-66
  4. J. Benavente, J. Martínez-Costas
    Pages 67-85
  5. P. Roy, R. Noad
    Pages 87-116
  6. K. M. Coombs
    Pages 117-167
  7. J. T. Patton, L. S. Silvestri, M. A. Tortorici, R. Vasquez-Del Carpio, Z. F. Taraporewala
    Pages 169-187
  8. J. B. Pesavento, S. E. Crawford, M. K. Estes, B. V. Venkataram Prasad
    Pages 189-219
  9. D. I. Stuart, J. M. Grimes
    Pages 221-244
  10. Back Matter
    Pages 263-268

About this book


Reoviridae family members are large, complex viruses that infect human, animals, plants and insects. They are unique in that they lack lipid envelopes and package their genomes of discrete double-stranded segments of RNA within multi-layered capsids. Lack of a lipid envelope has allowed three-dimensional structures of these large complex viruses to be obtained. The capsids of these viruses undergo cell entry, uncoating, the enzymatic functions necessary for transcription of the genome, and are later involved in egress from host cells. Recent years have seen an increase in our knowledge of the structure of these viruses coupled with substantial progress in unravelling the molecular details of these processes. Intriguingly, despite their diversity in hosts, structures and modes of transmission, striking parallels have emerged in the molecular interactions necessary for the essential processes of virus entry, assembly and release.

This book reviews our current understanding of Reoviridae entry, disassembly/assembly and egress in addition to updating high resolution structures of viral proteins and capsids from three different genera of the family.


avian reoviruses gastroenteritis infectious diarrhea mammalian orthoreoviruses rotaviral protein trafficking rotaviruses virology viroplasm

Editors and affiliations

  • Polly Roy
    • 1
  1. 1.Department of Infectious and Tropical DiseasesLondon School of Hygiene and Tropical MedicineLondonUK

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