About this book
The present study pursues the hypothesis that local compressive force and the occurrence of cartilage-specific transformation processes within tendons and ligaments are directly correlated.
In selected anatomical samples of human origin the distribution pattern of certain components of the extracellular matrix is assessed. Investigations are carried out at the extensor tendons of toes and fingers, at the transverse ligament of the atlas, at the transverse ligament of the acetabulum, and at the tendon of the superior oblique muscle and its trochlea. The molecular components of the extracellular matrix are detected with standardized immunohistochemical methods.
The results show that certain molecules only occur due to compressive stress, others due to tensile stress. The molecular spectrum of the extracellular matrix allows qualifying conclusions to the mechanical situation of a given part of the tissue.
The spatial expansion of the fibrocartilaginous adaptation zones in tendons and ligaments roughly corresponds with the zones subjected to compressive force; tensile stress alone does not result in a production of fibrocartilage.
- Book Title Molecular Parameters Indicating Adaptation to Mechanical Stress in Fibrous Connective Tissue
- Series Title Advances in Anatomy Embryology and Cell Biology
- DOI https://doi.org/10.1007/3-540-27832-X
- Copyright Information Springer-Verlag Berlin Heidelberg 2005
- Publisher Name Springer, Berlin, Heidelberg
- eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
- Softcover ISBN 978-3-540-24474-5
- eBook ISBN 978-3-540-27832-0
- Series ISSN 0301-5556
- Edition Number 1
- Number of Pages VI, 74
- Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
- Buy this book on publisher's site