© 2005

Developmental Biology of Neoplastic Growth

  • Alvaro Macieira-Coelho

Part of the Progress in Molecular and Subcellular Biology book series (PMSB, volume 40)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Janni Vestergaard, Mads Bak, Lars Allan Larsen
    Pages 1-28
  3. Pinella Buongiorno, Bharati Bapat
    Pages 29-53
  4. Tohru Kimura, Kazushige Murayama, Toshinobu Nakamura, Shoko Watanabe, Hiroki Umehara, Maya Tomooka et al.
    Pages 133-150
  5. Rachel H. Giles, Emile E. Voest
    Pages 151-181
  6. W.A. Ricke, Y. Wang, T. Kurita, S.W. Hayward, G.R. Cunha
    Pages 183-216
  7. Back Matter
    Pages 251-253

About this book


In this book, tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers illustrates how clinical incidence can be just the visible part of the iceberg, while the first changes at the tissue level sometimes occur several years before tumour growth becomes manifest. Several mechanisms are proposed to explain the distribution of cancers during the human life span and the decline of the incidence of cancers during human senescence.


Cancer Research Development Stem Cells Telomeres developmental biology regulation senescence tissue

Editors and affiliations

  • Alvaro Macieira-Coelho
    • 1
  1. 1.INSERMVersaillesFrance

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