MR Imaging in White Matter Diseases of the Brain and Spinal Cord

  • Massimo Filippi
  • Nicola De Stefano
  • Vincent Dousset
  • Joseph C. McGowan

Part of the Medical Radiology Diagnostic Imaging book series (MEDRAD)

Table of contents

  1. Front Matter
    Pages I-XI
  2. MR Techniques: Principles

    1. Mark A. Horsfield
      Pages 3-12
    2. Kenneth W. Fishbein, Joseph C. McGowan, R. G. Spencer
      Pages 13-28
    3. Dara L. Kraitchman
      Pages 29-40
    4. Joseph C. McGowan
      Pages 41-55
    5. Joseph C. McGowan
      Pages 57-62
    6. Peter C.M. van Zijl, Lidia Nagae-Poetscher, Susumu Mori
      Pages 63-81
    7. Scott D. Swanson
      Pages 83-91
    8. P. Jezzard, A. Toosy
      Pages 93-110
    9. Robert E. Lenkinski
      Pages 115-127
  3. Disorders of Myelination

    1. Charles Raybaud
      Pages 151-175
    2. Nicola De Stefano, Marzia Mortilla
      Pages 195-207
  4. Demyelinating Diseases

    1. A. Traboulsee, David K.B. Li, G. Zhao, Donald W. Paty
      Pages 211-223
    2. Massimo Filippi, Maria A. Rocca
      Pages 225-240
    3. Jack H. Simon, Bette K. Kleinschmidt-DeMasters
      Pages 241-253
    4. Stefan Schwarz, Michael Knauth
      Pages 255-266
    5. Roland Bammer, Franz Fazekas, Siegrid Strasser-Fuchs
      Pages 269-277
    6. Simon J. Hickman, David H. Miller
      Pages 279-289
  5. Immune-Mediated Disorders

    1. Darin T. Okuda, Timothy L. Vollmer
      Pages 293-310
    2. Bart J. Emmer, Tom W.J. Huizinga, Mark A. van Buchem
      Pages 311-329
    3. Marco Rovaris, Massimo Filippi
      Pages 343-352
  6. White Matter Disorders Related with Aging

    1. Giovanni B. Frisoni
      Pages 355-361
    2. Joao A. Gomes, Louis R. Caplan
      Pages 363-375
  7. White Matter Changes Secondary to Other Conditions

    1. Alberto Bizzi, Bianca Pollo, Carlo Marras
      Pages 411-439
    2. Zee Chi-Shing, Marcel Maya, John L. Go, Paul E. Kim, Ilhami Kovanlikaya
      Pages 441-451
    3. Fabio Sambataro, Alessandro Bertolino
      Pages 453-464
  8. Back Matter
    Pages 465-477

About this book


In recent decades, the use of neuroimaging techniques has resulted in outstanding progress in the diagnosis and management of neurological diseases, and this is particularly true of those diseases that affect the white matter of the brain and spinal cord. This book, written by internationally acclaimed experts, comprises a series of comprehensive and up-to-date reviews on the use of MR imaging in these major neurological conditions. The diverse available MR techniques, such as magnetization transfer MRI, diffusion-weighted MRI, MR spectroscopy, functional MRI, cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, offer an extraordinarily powerful means of gaining fundamental in vivo insights into disease processes. The strengths and weaknesses of all these techniques in the study of multiple sclerosis and other relevant diseases are extensively considered. After an introductory section on neuroimaging technology, subsequent sections address disorders of myelination, demyelinating diseases, immune-mediated disorders, and white matter disorders related to aging and other conditions. This book provides a valuable summary of the state of the art in the field, and defines important areas for future research.


MR imaging MRI Nervous System brain diagnosis magnetic resonance magnetic resonance imaging magnetic resonance imaging (MRI) molecular imaging neuroimaging spinal cord trauma white matter diseases

Editors and affiliations

  • Massimo Filippi
    • 1
  • Nicola De Stefano
    • 2
  • Vincent Dousset
    • 3
  • Joseph C. McGowan
    • 4
  1. 1.Neuroimaging Research Unit Department of Neurology Scientific InstituteUniversity Ospedale San RaffaeleMilanItaly
  2. 2.Department of Neurology & Behavioral SciencesUniversity of SienaSienaItaly
  3. 3.Service de Neuroradiologie Diagnostique et Thérapeutique CHU Bordeaux Pellegrin and Laboratoire de Neurobiologie des Affections de la MyélineUniversité Victor SegalenBordeauxFrance
  4. 4.Department of Electrical EngineeringUnited States Naval AcademyAnnapolisUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2005
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-540-40230-5
  • Online ISBN 978-3-540-27644-9
  • Series Print ISSN 0942-5373
  • Buy this book on publisher's site
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