Gene Therapy of Autoimmune Diseases

  • Gérald J. Prud’homme

Part of the Medical Intelligence Unit book series (MIUN)

Table of contents

  1. Front Matter
    Pages I-X
  2. Roberto Furlan, Erica Butti, Stefano Pluchino, Gianvito Martino
    Pages 1-16
  3. Jon D. Piganelli, Massimo Trucco, Nick Giannoukakis
    Pages 17-42
  4. Ciriaco A. Piccirillo, Argyrios N. Theofilopoulos, Gérald J. Prud’homme
    Pages 43-70
  5. Justin M. Johnson, Vincent K. Tuohy
    Pages 71-88
  6. Natacha Bessis, Marie-Christophe Boissier
    Pages 89-100
  7. Moustapha El-Amine, Mary Litzinger, Marco E. F. Melo, David W. Scott
    Pages 101-111
  8. Gérald J. Prud’homme, Yelena Glinka, Yigang Chang, Xiaoying Li
    Pages 112-136
  9. Back Matter
    Pages 137-138

About this book


Autoimmune diseases are diverse and responsible for considerable morbidity. Their etiology remains largely unknown, and current therapy with anti-inflammatory drugs is prone to adverse effects, and rarely curative. New therapies with anti-cytokine antibodies or receptors are promising, but require frequent administration of expensive protein drugs.

Gene Therapy of Autoimmune Diseases comprehensively reviews research in gene therapy for autoimmune diseases with viral or non-viral vectors. Gene therapy offers the possibility of long-term, continuous delivery of a wide variety of immunosuppressive, anti-inflammatory, or tolerance-inducing agents. Moreover, highly specific genetically modified cells can be produced. This book discusses the most promising avenues in this exciting new field.


Antigen DNA autoimmune disease gene therapy gene transfer genes molecular biology

Authors and affiliations

  • Gérald J. Prud’homme
    • 1
  1. 1.Department of Laboratory Medicine and PathobiologyUniversity of Toronto St. Michael’s HospitalTorontoCanada

Bibliographic information

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Health & Hospitals