© 2001

Human Cell Culture

Primary Mesenchymal Cells

  • Manfred R. Koller
  • Bernhard O. Palsson
  • John R.W. Masters

Part of the Human Cell Culture book series (HUCC, volume 5)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Ross Tubo, Liesbeth Brown
    Pages 1-16
  3. Louis C Almekinders, Albert J Banes
    Pages 17-25
  4. Thomas Oates Jr, Anh M Hoang
    Pages 27-41
  5. Diane Proudfoot, Catherine M Shanahan
    Pages 43-64
  6. Peter F M van der Ven
    Pages 65-101
  7. Ren-Ke Li
    Pages 103-124
  8. Jonathan Mansbridge
    Pages 125-172
  9. Louise J Hutley, Felicity S Newell, Steven J Suchting, Johannes B Prins
    Pages 173-187
  10. Mark F Pittenger, Gabriel Mbalaviele, Marcia Black, Joseph D Mosca, Daniel R Marshak
    Pages 189-207
  11. Jason Chesney, Richard Bucala
    Pages 209-219
  12. Lucy Di-Silvio, Neelam Gurav
    Pages 221-241
  13. Back Matter
    Pages 242-244

About this book


The human body contains many specialized tissues that are capable of fulfilling an incredible variety of functions necessary for our survival. This volume in the Human Cell Culture Series focuses on mesenchymal tissues and cells. The in vitro study of mesenchymal cells is perhaps the oldest form of human cell culture, beginning with the culturing of fibroblasts. Fibroblasts have long been generically described in the literature, arising from many tissue types upon in vitro cell culture. However, recent studies, many enabled by new molecular biology techniques, have shown considerable diversity in fibroblast type and function, as described within this volume. Mesenchymal tissue types that are described within include bone, cartilage, tendons and ligaments, muscle, adipose tissue, and skin (dermis). The proper function of these tissues is predominantly dependent upon the proper proliferation, differentiation, and function of the mesenchymal cells which make up the tissue. Recent advancements in primary human mesenchymal cell culture have led to remarkable progress in the study of these tissues. Landmark experiments have now demonstrated a stem cell basis for many of these tissues, and, furthermore, significant plasticity and inter-conversion of stem cells between these tissues, resulting in a great deal of contemporary excitement and controversy. Newly-developed mesenchymal cell culture techniques have even lead to novel clinical practices for the treatment of disease.


Stent bioengineering bone cartilage cells methodology skeletal muscle smooth muscle tissue

Editors and affiliations

  • Manfred R. Koller
    • 1
  • Bernhard O. Palsson
    • 2
  • John R.W. Masters
    • 3
  1. 1.OncosisSan DiegoUSA
  2. 2.Department of BioengineeringUniversity of CaliforniaSan DiegoUSA
  3. 3.University College LondonLondonUK

Bibliographic information