Abstract
The objective of the study is themass spectrometry analysis of the protein composition in blood plasma samples of large intestine cancer patients. Protein profiles of 58 blood plasma samples of large intestine cancer patients and healthy volunteers are analyzed using ultrahigh-resolution panoramic mass spectrometry. It is shown that the coincidence of identifications in the protein composition samples of intestine cancer patients and healthy men is 60–80%. Samples of intestines cancer patients contain proteins involved in the interaction with ribonucleic acid, proteins, and lowmolecular substrata.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
S. Y. Zhang, M. Lin, and H. B. Zhang, Int. J. Clin. Exp. Pathol. 8, 9404 (2015).
I. Butvilovskaya, S. B. Popletaeva, V. R. Chechetkin, et al., Cancer Med. 5, 1361 (2016).
A. L. Kaysheva, A. T. Kopylov, T. O. Pleshakova, et al., Biotecnologia Aplicada 34, 2211 (2017).
A. L. Kaysheva, A. T. Kopylov, I. Y. Yurov, et al., Voprosy Prakticheskoi Pediatrii 11(5), 12 (2016).
A. L. Kaysheva, A. T. Kopylov, E. A. Ponomarenko, et al., J. Mol. Neurosci. 64, 440 (2018).
K. Kandasamy, A. Pandey, and H. Molina, Analyt. Chem. 81, 7170 (2009).
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © A.L. Kaysheva, A.T. Kopylov, T.O. Pleshakova, N.E. Kushlinskii, V.G. Nikitaev, E.A. Druzhinina, A.I. Archakov, Yu.D. Ivanov, 2018, published in Kratkie Soobshcheniya po Fizike, 2018, Vol. 45, No. 9, pp. 34–38.
About this article
Cite this article
Kaysheva, A.L., Kopylov, A.T., Pleshakova, T.O. et al. Mass Spectrometry Profiling of the Protein Composition of Blood Plasma of Colorectal Cancer Patients. Bull. Lebedev Phys. Inst. 45, 279–281 (2018). https://doi.org/10.3103/S1068335618090051
Received:
Published:
Issue Date:
DOI: https://doi.org/10.3103/S1068335618090051