Bulletin of the Lebedev Physics Institute

, Volume 45, Issue 7, pp 204–208 | Cite as

Numerical Simulation Optimization of Selective Heating of Blood Vessels in “Port-Wine Stains” under Laser Irradiation in Various Modes

  • I. V. PonomarevEmail author
  • S. B. Topchiy
  • M. A. Kazaryan
  • A. E. Pushkareva
  • S. V. Klyuchareva


Numerical simulation of blood vessel heating is used to select the most efficient and safe methods of laser treatment of “port-wine stains”. Selective heating under radiation is calculated for a 980-nm diode laser, a Nd:YAG laser, a copper vapor laser (CVL), and a pulsed dye laser (PDL). The energy exposure range (fluence), the diameter and depth of vessels, at which their selective heating to the coagulation temperature is possible, are determined.


copper vapor laser pulsed dye laser port-wine stains laser therapy vascular malformations selective vessel heating 


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  1. 1.
    S. H. Barsky, S. Rosen, D. E. Geer, and J. M. Noe, J. Invest. Dermatol. 74(3) 154 (1980).CrossRefGoogle Scholar
  2. 2.
    M. M. Selim et al., Dermatol. Surg. 30, 892 (2004).Google Scholar
  3. 3.
    R. R. Anderson and J. A. Parrish, Lasers Surg. Med. 1, 263 (1981).CrossRefGoogle Scholar
  4. 4.
    G. B. Al’tshuller, M. Z. Smirnov, and A. E. Pushkareva, Opt. Spektrosk. 97, 151 (2004) [Opt. Spectrosc. 97, 141 (2004)].ADSGoogle Scholar
  5. 5.
    A. E. Pushkareva, I. V. Ponomarev, A. A. Isaev, and S. V. Klyuchareva, Laser Phys. 28, 1 (2018).Google Scholar
  6. 6.
    A. Roggan, M. Friebel, K. Doershel, et al., J. Biomed. Opt. 4, 36 (1999).ADSCrossRefGoogle Scholar
  7. 7.
    L. F. A. Douven and G. W. Lucassen, Proc. SPIE 3914, 312 (2000).ADSCrossRefGoogle Scholar
  8. 8.
    Optical-Thermal Response of Laser-Irradiated Tissue. Ed. by A. J. Welch and M. J. C. van Gemert (Plenum Press, N.Y., 1995).Google Scholar
  9. 9.
    M. J. C. van Gemert, S. L. Jacques, H. J. C. M. Sterenborg, and W. M. Star, Skin Optics, IEEE Trans. Biomed. Eng. 36(12), 1146(1989).CrossRefGoogle Scholar
  10. 10.
    A. N. Takata, L. Zaneveld, and W. Richter, Report SAM-TR-77-38 (Brooks Air Force Base, TX: US Air Force School of AerospaceMedicine, 1977).Google Scholar
  11. 11.
    K. Giering, I. Lamprecht, and O. Minet, Proc. SPIE 2624, 188 (1995).ADSCrossRefGoogle Scholar
  12. 12.
    K. M. Sekins and A. F. Emery, in Therapeutic Heat and Cold. Ed. by J. F. Lehmann (Williams and Wilkins, Baltimore/London, 1982).Google Scholar
  13. 13.
    Y. Zhou et al., Exp. Theor. Med. 4(6), 1017 (2012).CrossRefGoogle Scholar
  14. 14.
    G. Lucassen et al., Lasers Surg.Med. 18(4), 345 (1996).CrossRefGoogle Scholar
  15. 15.
    R. A. Neumann, R. M. Knobler, H. Leonhartsberger, and W. Gebhart, J. Invest. Dermatol. 99, 160 (1992).CrossRefGoogle Scholar
  16. 16.
    O. Tan, P. Morrison, and A. Kurban, Plast. Reconstr. Surg. 86, 1112 (1990).CrossRefGoogle Scholar
  17. 17.
    M. Waner, S. Dinehart, M. Wilson, and S. Flock, J. Dermatol. Surg. Oncol. 19, 992 (1993).CrossRefGoogle Scholar
  18. 18.
    S. V. Klyuchareva, I. V. Ponomarev, and A. E. Pushkareva, Vestnik Dermatologii i Veneroologii 94, 67 (2018).CrossRefGoogle Scholar
  19. 19.
    S. E. McCoy, Lasers Surg.Med. 21, 329 (1997). BULLETINCrossRefGoogle Scholar

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© Allerton Press, Inc. 2018

Authors and Affiliations

  • I. V. Ponomarev
    • 1
    Email author
  • S. B. Topchiy
    • 1
  • M. A. Kazaryan
    • 1
  • A. E. Pushkareva
    • 2
  • S. V. Klyuchareva
    • 3
  1. 1.Lebedev Physical InstituteRussian Academy of SciencesMoscowRussia
  2. 2.Saint Petersburg National Research University of Information Technologies, Mechanics and OpticsSt. PetersburgRussia
  3. 3.Mechnikov North-Western State Medical UniversitySt. PetersburgRussia

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