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Determination of Codeine Phosphate in the Culture Fluid of Rhodococcus by High-Performance Liquid Chromatography

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Abstract

The conditions for the quantitative determination of codeine phosphate in the culture fluid of Rhodococcus by reversed-phase high-performance liquid chromatography (RP-HPLC) are established. The specificity, linearity, precision, and accuracy of the method are confirmed by the validation procedure.

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Correspondence to E. V. Vikhareva.

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Original Russian Text © A.N. Plotnikov, Yu.N. Karpenko, E.V. Vikhareva, E.A. Tyumina, M.I. Richkova, A.A. Selyaninov, 2018, published in Vestnik Moskovskogo Universiteta, Seriya 2: Khimiya, 2018, No. 1, pp. 50–55.

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Plotnikov, A.N., Karpenko, Y.N., Vikhareva, E.V. et al. Determination of Codeine Phosphate in the Culture Fluid of Rhodococcus by High-Performance Liquid Chromatography. Moscow Univ. Chem. Bull. 72, 328–332 (2017). https://doi.org/10.3103/S0027131418010054

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  • DOI: https://doi.org/10.3103/S0027131418010054

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