Moscow University Chemistry Bulletin

, Volume 72, Issue 6, pp 255–259 | Cite as

Gradient HPLC Separation of Alkylphosphonic Acids on a Hypercarb Porous Graphitic Carbon Adsorbent with an Aqueous Formic Acid Solution as the Mobile Phase

  • E. N. Goncharova
  • I. P. Semenova
  • M. A. Statkus
  • G. I. Tsysin


An approach to the gradient HPLC separation of alkylphosphonic acids on a Hypercarb porous graphitic carbon adsorbent with an aqueous formic acid solution as a mobile phase is proposed. Analytes were detected using a quadrupole mass spectrometer. To increase the retention of the analytes, the chromatographic column was washed with water before the injection of a sample solution. This procedure results in a three- to fourfold increase in the retention factors of alkylphosphonic acids in comparison with the analogs described in the publications.


liquid chromatography (HPLC) mass spectrometry Hypercarb porous graphitic carbon adsorbent alkylphosphonic acids 


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Copyright information

© Allerton Press, Inc. 2017

Authors and Affiliations

  • E. N. Goncharova
    • 1
  • I. P. Semenova
    • 1
  • M. A. Statkus
    • 1
  • G. I. Tsysin
    • 1
  1. 1.Department of ChemistryMoscow State UniversityMoscowRussia

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