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Intellectual Mining of Patient Data with Melanoma for Identification of Disease Markers and Critical Genes

  • D. K. ChebanovEmail author
  • I. N. MikhailovaEmail author
THE JSM METHOD OF AUTOMATED RESEARCH SUPPORT AND ITS APPLICATION IN INTELLIGENT SYSTEMS FOR MEDICINE
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Abstract

Genotypic (DNA mutations) and phenotyping data on patients with melanoma are analyzed to identify markers of early disease diagnosis and critical involved genes. An optimal mining method was chosen from those that are traditionally used in the field. This method allows one to analyze a set of terms. Automatic and interactive approaches were performed, which both allow a considerable reduction in the computational requirements. New melanoma-associated genes and candidate relapse markers were identified. Data mining was performed with the JSM method of automated support of scientific research (JSM ASSR).

Keywords:

artificial intelligence oncology genotypic data phenotypic data mutations JSM ASSR method 

Notes

ACKNOWLEDGMENTS

The authors are grateful to Mikhail I. Zabezhailo for valuable recommendations and ideas.

CONFLICT OF INTEREST

The authors declare that they have no conflicts of interest.

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Copyright information

© Allerton Press, Inc. 2019

Authors and Affiliations

  1. 1.Russian State University for the HumanitiesMoscowRussia
  2. 2.Blokhin National Medical Research Center for Oncology, Ministry of Health of the Russian FederationMoscowRussia

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