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Development of an effective extraction process for coenzyme Q10 from Artemia

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Abstract

A method for extracting coenzyme Q10 (CoQ10) from Artemia was developed. 1 g of fresh Artemia was incubated with 75 % acetic acid at (30 ± 2)°C for 24 h, followed by three consecutive extractions with a mixture of 5 mL of hexane and 5 mL of ethanol, then analysis by a validated high-performance liquid chromatography with a diode-array detector. The calibration curve for CoQ10 was linear in a range of 1–50 μg mL−1. The limits of detection and quantification were 0.3 μg mL−1 and 1.1 μg mL−1, respectively. Mean recoveries were 94–100 % with a high precision of below 10 %. The method developed was found to be simple, efficient and the time required for releasing CoQ10 from Artemia was short. The method provides not only low energy consumption but is also practical for industrial applications.

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Authors and Affiliations

  1. Department of Chemistry and Centre of Excellence for Innovation in Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla, 90112, Thailand

    Thitima Rujiralai & Nirundorn Raekasin

  2. Department of Science, Prince of Songkla University, Pattani campus, Muang, Pattani, 94000, Thailand

    Wilairat Cheewasedtham

  3. Department of Technology and Industry, Faculty of Science and Technology, Prince of Songkla University, Pattani campus, Muang, Pattani, 94000, Thailand

    Chonlatee Cheewasedtham

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  1. Thitima Rujiralai
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  2. Nirundorn Raekasin
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  3. Wilairat Cheewasedtham
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  4. Chonlatee Cheewasedtham
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Correspondence to Thitima Rujiralai.

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Rujiralai, T., Raekasin, N., Cheewasedtham, W. et al. Development of an effective extraction process for coenzyme Q10 from Artemia . Chem. Pap. 68, 1041–1048 (2014). https://doi.org/10.2478/s11696-014-0558-2

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