Skip to main content
SpringerLink
Log in

Anti-oxidative properties of bi-1,2,4-triazine bisulphides

  • Short Communication
  • Published:
Chemical Papers Aims and scope Submit manuscript

Abstract

The anti-oxidative properties of bitriazines (BTs) were evaluated using HPLC and cyclic voltammetry. In the first case, a RP-HPLC assay was made, using a fluorescence detector, hydroxyl radicals generated in Fenton reaction, and terephthalic acid as a spin trap. The measurements were performed using aqueous or methanolic solutions. It was found that when the BTs were dissolved in water they were antioxidants, while dissolved in methanol they were pro-oxidants. Their different physicochemical properties in both solvents were confirmed by voltammetric, chromatographic as well as spectrophotometric measurements.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • da Silva, G., Bozzelli, J. W., & Asatryan, R. (2009). Hydroxyl radical initiated oxidation of S-triazine: Hydrogen abstraction is faster than hydroxyl addition. The Journal of Physical Chemistry A, 113, 8596–8606. DOI: 10.1021/jp904156r.

    Article  Google Scholar 

  • do Nascimento, P. C., Bohrer, D., de Carvalho, L. M., Trevisan, J., Pilau, E. J., Vendrame, Z. B., & Dessuy, M. B. (2003). Determination of triazines in hemodialysis saline solutions by adsorptive stripping voltammetry after extraction in acetonitrile. Journal of the Brazilian Chemical Society, 14, 577–583. DOI: 10.1590/s0103-50532003000400014.

    Article  Google Scholar 

  • Głód, B. K., Piszcz, P., Czajka, K., & Zarzycki, P. K. (2011). A new total antioxidant potential measurements using RPHPLC assay with fluorescence detection. Journal of Chromatographic Science, 49, 401–404. DOI: 10.1093/chromsci/49.5.401.

    Article  Google Scholar 

  • Głód, B. K., Piszcz, P., Beta, A., & Zarzycki, P. K. (2012a). RP-HPLC, with fluorescence detection, assay for the determination of total antioxidant potential (TAP). Journal of Liquid Chromatography & Related Technologies, 35, 1194–1201. DOI: 10.1080/10826076.2011.619029.

    Article  Google Scholar 

  • Głód, B. K., Piszcz, P., Czajka, J., & Zarzycki, P. K. (2012b). Evaluation of total antioxidant potential of selected biogenic polyamines, non-alcoholic drinks and alcoholic beverages using improved RP-HPLC assay involving fluorescence detection. Food Chemistry, 131, 1029–1029. DOI: 10.1016/j.foodchem.2011.09.065.

    Google Scholar 

  • Gokel, G. W., Leevy, W. M., & Weber, M. E. (2004). Crown ethers: Sensors for ions and molecular scaffolds for materials and biological models. Chemical Reviews, 104, 2723–2750. DOI: 10.1021/cr020080k.

    Article  CAS  Google Scholar 

  • Keefe, M. H., Benkstein, K. D., & Hupp, J. T. (2000). Luminescent sensor molecules based on coordinated metals: a review of recent developments. Coordination Chemistry Reviews, 205, 201–228. DOI: 10.1016/s0010-8545(00)00240-x.

    Article  CAS  Google Scholar 

  • Ławecka, J., Olender, E., Piszcz, P., & Rykowski, A. (2008). Sequential homo-coupling Diels-Alder/retro Diels-Alder reaction of 5,5′-bi-1,2,4-triazine-containing thiamacrocycles as a new route to thiacrown ethers incorporating a 2,2′-bipyridine subunit. Tetrahedron Letters, 49, 723–726. DOI: 10.1016/j.tetlet.2007.11.138.

    Article  Google Scholar 

  • Ławecka J., Karczmarzyk, Z., Wolińska, E., Olender, E., Branowska, D., & Rykowski, A. (2011). A novel approach to conformationally strained 2,2′-bipyridine thiacrown ethers and their chiral sulfoxides by sequential homo-coupling/DA-rDA reaction of 5,5′-bi-1,2,4-triazine-containing thiamacrocycles. Tetrahedron, 67, 3098–3104. DOI: 10.1016/j.tet.2011.02.081.

    Article  Google Scholar 

  • Lehn, J. M. (1995). Supramolecular chemistry. Concepts and perspectives. Weinheim, Germany: VCH.

    Book  Google Scholar 

  • Malkov, A. V., & Kočovský, P. (2007). Chiral N-oxides in asymmetric catalysis. European Journal of Organic Chemistry, 2007, 29–36. DOI: 10.1002/ejoc.200600474.

  • Pomeranc, D., Heitz, V., Chambrom, J. C., & Sauvage, J. P. (2001). Octahedral Fe(II) and Ru(II) complexes based on a new bis 1,10-phenanthroline ligand that imposes a well defined axis. Journal of the American Chemical Society, 123, 12215–12221. DOI: 10.1021/ja011250y.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Faculty of Science, Institute of Chemistry, Department of Analytical Chemistry, Siedlce University of Natural Sciences and Humanities, 3 Maja 54, 08-110, Siedlce, Poland

    Paweł Piszcz & Bronisław K. Głód

Authors
  1. Paweł Piszcz
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Bronisław K. Głód
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Bronisław K. Głód.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Piszcz, P., Głód, B.K. Anti-oxidative properties of bi-1,2,4-triazine bisulphides. Chem. Pap. 67, 764–768 (2013). https://doi.org/10.2478/s11696-013-0355-3

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2478/s11696-013-0355-3

Keywords

Search

Navigation