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Stereoselective synthesis of the polar part of mycestericins E and G

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Abstract

5-O-(t-Butyldimethylsilyl)-3-deoxy-3-C-hydroxymethyl-1,2-O-isopropylidene-3-(methoxycarbonylamino)-α-d-xylofuranose IV has been proved to be an appropriate building block in the stereoselective synthesis of methyl (4S)-4-[(1′R)-1′-acetoxy-4′-oxobutyl]-3-benzyl-2-oxooxazolidine-4-carboxylate III representing the polar part of the naturally occurring mycestericins E and mycestericins G.

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Authors and Affiliations

  1. Department of Organic Chemistry, Institute of Chemical Sciences, P. J. Šafárik University, Moyzesova 11, 040 01, Košice, Slovakia

    Miroslava Martinková, Jozef Gonda, Alena Uhríková & Margaréta Kováčvá

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  1. Miroslava Martinková
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  2. Jozef Gonda
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  3. Alena Uhríková
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  4. Margaréta Kováčvá
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Correspondence to Miroslava Martinková.

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Martinková, M., Gonda, J., Uhríková, A. et al. Stereoselective synthesis of the polar part of mycestericins E and G. Chem. Pap. 65, 527–535 (2011). https://doi.org/10.2478/s11696-011-0030-5

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  • DOI: https://doi.org/10.2478/s11696-011-0030-5

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