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An efficient and novel one-pot synthesis of 2,4,5-triaryl-1H-imidazoles catalyzed by UO2(NO3)2·6H2O under heterogeneous conditions

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Abstract

An efficient, convenient, and novel one-pot method of 2,4,5-triaryl-1H-imidazoles synthesis using benzil, arene carbaldehydes, and ammonium acetate, catalyzed by uranyl nitrate hexahydrate [UO2(NO3)2·6H2O] supported on acidic alumina and resulting in good to excellent yields under heterogeneous conditions, is reported. Formation of a reactants-catalyst complex was confirmed by UV-VIS spectral data. Antibacterial (MIC) and antioxidant activity of the synthesized compounds was also studied.

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  1. Chemistry Division, School of Advanced Sciences, VIT University, Vellore, 632014, India

    Vardhineedi Sri Venkata Satyanarayana & Amaravadi Sivakumar

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  1. Vardhineedi Sri Venkata Satyanarayana
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  2. Amaravadi Sivakumar
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Correspondence to Amaravadi Sivakumar.

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Satyanarayana, V.S.V., Sivakumar, A. An efficient and novel one-pot synthesis of 2,4,5-triaryl-1H-imidazoles catalyzed by UO2(NO3)2·6H2O under heterogeneous conditions. Chem. Pap. 65, 519–526 (2011). https://doi.org/10.2478/s11696-011-0028-z

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