New targets may lead to novel classes of anti-obesity drugs
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Although a number of appetite suppressants are now in clinical trials, the search for new anti-obesity drug targets continues. Recent advances in basic science have unveiled 2 new receptors that may prove to have potential in this field. They are the neuropeptide Y (NPY)-5 receptor and the peroxisome proliferator activated receptor (PPAR)-γ. These possible new approaches to the treatment of obesity were discussed at the 3rd IBC USA conference on ‘Obesity - Advances in Understanding and Treatment’ [ San Diego, US; September 1996 ].