New era of combination therapy for HIV infection
Reducing viral load to undetectable levels in patients with HIV infection has been achieved using a number of drug combinations, according to the results of studies presented at the 11th International Conference on AIDS [ Vancouver, Canada; July 1996 ]. In one study, plasma levels were still below the level of detection after 1 year of treatment with zidovudine, zalcitabine and nevirapine. Such studies herald a new era of hope for patients with HIV infection. As recently as last year, viewing HIV infection as a manageable chronic disease was considered unrealistic, but now it appears to be a real possibility. Future research must now concentrate on determining whether viral suppression can be maintained in the long term, and on the effects of combination treatments on clinical outcome.
KeywordsViral Load Lamivudine Zidovudine Ritonavir Nevirapine
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