Inpharma Weekly

, Volume 1005, Issue 1, pp 9–10 | Cite as

Novel local delivery strategies for preventing restenosis

  • Jo Barnes
Newsletter Article


Local delivery of biologically active agents is a promising approach to preventing restenosis, according to data presented at the 17th Congress of the European Society of Cardiology [ Amsterdam, The Netherlands; August 1995 ]. US researchers aim to improve upon existing local delivery techniques by using biodegradable polymeric nanoparticles as a carrier for drugs which prevent neointimal proliferation. Other researchers have developed a fibrin adhesive capable of attaching endothelial cells to damaged arterial walls. Findings from preclinical studies with these strategies and their potential for clinical application were discussed at the meeting.


Percutaneous Translumina1 Coronary Angioplasty Local Delivery PLGA Nanoparticles Local Drug Delivery Neointimal Proliferation 
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Copyright information

© Adis International Ltd 1995

Authors and Affiliations

  • Jo Barnes

There are no affiliations available

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