Question mark over constant aciclovir therapy for recurrent genital herpes
Some experts are arguing for more widespread use of aciclovir in recurrent genital herpes. The aim of this change to practice is to further reduce the risk of herpes simplex virus-2 (HSV-2) transmission. The belief that this can be achieved with continuous aciclovir treatment is largely due to the results of a recent study that showed a reduction in asymptomatic shedding of HSV-2 in aciclovir recipients. However, Dr Raj Patel from Southampton University Hospitals, UK, claimed that the available evidence is insufficient, and that suppressive aciclovir therapy should only be used when symptoms recur. Both sides of the argument were debated at the 7th European Congress of Clinical Microbiology and Infectious Disease [ Vienna, Austria; March 1995 ].