Peptide-based EBV vaccine in phase I trial

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The first clinical study of a synthetic peptide-based vaccine against the Epstein-Barr virus (EBV) is now underway. Researchers are hopeful that the vaccine, which contains a cytotoxic T-lymphocyte (CTL) epitope, may protect against EBV immunopathology. Inpharma spoke to Dr Andreas Suhrbier, from the Queensland Institute of Medical Research, Brisbane, Australia, about the current phase I trial and the potential applications for an EBV vaccine in protecting against infectious mononucleosis (glandular fever) and the development of post-transplant lymphoproliferative disease (PTLD).