American Journal of Clinical Dermatology

, Volume 8, Issue 6, pp 365–369 | Cite as

Non-Melanocytic Benign Skin Tumors in Children

  • Ana Lucas
  • Isabel Betlloch
  • Maria Planelles
  • Teresa Martínez
  • Maria Péerez-Crespo
  • Javier Mataix
  • Isabel Belinchón
Original Research Article


Background: Dermatologists often attend children with benign skin tumors and cysts. The decision to perform dermatologic surgery in children may be difficult to make, especially in cases of benign tumors.

Objective: The objective of this study was to determine the nature of non-melanocytic benign skin tumors amenable to dermatologic surgery in children.

Methods: Histopathologic studies of skin tumors in children treated by our department between January 2004 and December 2005 were studied. Malignant and melanocytic tumors were excluded. Age, sex, type of tumor, diagnostic category, site, size, reason for removal, type of anesthesia, and any other associated disorders were recorded.

Results: The records revealed that 121 patients presented 129 non-melanocytic benign skin tumors (73 in boys and 56 in girls). A total of 27 different anatomopathologic diagnoses were found. The most frequent was pilomatrixoma with 27 cases (20.9%), followed by infundibular cyst with 14 (10.9%), and molluscum contagiosum with 13 (10.1%). Tumors were located on the head and neck (45.7%), trunk (34.1%), and limbs (20.1%). The most frequently affected age group was children aged 11–14 years, which included 50 patients (38.8%). The main type of anesthesia used was local in 54.6% of the cases, sedation plus local anesthesia in 39.7%, and general anesthesia in 5.7%. The reasons that led to removal of the tumors were: increase in the size of the tumor (49%); various types of discomfort, such as severe itching or pain (30%); parental concern (4%); diagnostic uncertainty (16%); and esthetic reasons (1%).

Conclusion: There is a wide diversity of non-melanocytic benign skin tumors in children, some of which require surgical treatment. Pilomatrixomas appear to be the most frequent benign tumors; there are also high frequencies of infundibular cysts, pyogenic granulomas, and viral tumors. Most can be removed under local anesthesia, with or without sedation.


Sebaceous Gland Myotonic Dystrophy Melanocytic Nevus Pyogenic Granuloma Molluscum Contagiosum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



No sources of funding were used to assist in the preparation of this study. The authors have no conflicts of interest that are directly relevant to the content of this study.


  1. 1.
    Abensour M, Grosshans E. Cutaneous tumors and adnexal cyst in children. Ann Dermatol Venereol 1989; 116: 333–9PubMedGoogle Scholar
  2. 2.
    Barranger C, Morel P, Civatte J. Cutaneous tumors in children. Rev Prat 1977; 27: 3321–30PubMedGoogle Scholar
  3. 3.
    Putnam TC. Lumps and bumps in children. Pediatr Rev 1992; 13: 371–8PubMedCrossRefGoogle Scholar
  4. 4.
    Filston HC. Common lumps and bumps of the head and neck in infants and children. Pediatr Ann 1989; 18: 180–2, 184, 186PubMedGoogle Scholar
  5. 5.
    Knight PJ, Reiner CB. Superficial lumps in children: what, when, and why? Pediatrics 1983; 72: 147–53PubMedGoogle Scholar
  6. 6.
    Bruckner AL, Frieden IJ. Hemangiomas of infancy. J Am Acad Dermatol 2003; 48: 477–93PubMedCrossRefGoogle Scholar
  7. 7.
    Fraitag S. Melanocytic nevi in children. Ann Pathol 2004; 24: 587–604PubMedCrossRefGoogle Scholar
  8. 8.
    Lyon VB. Lumps and bumps in children - when to worry: recent trends in recognition and pathology of hemangiomas of infancy and Spitz nevi. Curr Opin Pediatr 2004; 16: 392–5PubMedCrossRefGoogle Scholar
  9. 9.
    Pariser RJ. Benign neoplasms of the skin. Med Clin North Am 1998; 82: 1285–307PubMedCrossRefGoogle Scholar
  10. 10.
    Barro-Traore F, Traore A, Konate I, et al. Epidemiological features of tumors of the skin and mucosal membranes in the department of dermatology at the Yalgado Ouedraogo National Hospital, Ouagadougou, Burkina Faso. Sante 2003; 13:101–4Google Scholar
  11. 11.
    Pirouzmanesh A, Reinisch JF, Gonzalez-Gomez I, et al. Pilomatrixoma: a review of 346 cases. Plast Reconstr Surg 2003; 112: 1784–9PubMedCrossRefGoogle Scholar
  12. 12.
    Darwish AH, Al-Jalahema EK, Dhiman AK, et al. Clinicopathological study of pilomatricoma. Saudi Med J 2001; 22: 268–71PubMedGoogle Scholar
  13. 13.
    Cigliano B, Baltogiannis N, De Marco M, et al. Pilomatricoma in childhood: a retrospective study from three European paediatric centres. Eur J Pediatr 2005; 164: 673–7PubMedCrossRefGoogle Scholar
  14. 14.
    Vergara G, Betlloch I, Galiana I, et al. Tratamiento quir´ urgico de lesiones dermatol´ ogicas en pacientes pedi´ atricos. Actas Dermosifiliogr 2004; 95: 362–9Google Scholar
  15. 15.
    Cunningham BB, Gigler V, Wang K, et al. General anesthesia for pediatric dermatologic procedures: risks and complications. Arch Dermatol 2005; 141: 573–6PubMedCrossRefGoogle Scholar
  16. 16.
    Muñoz-Pérez MA, Garc´ia-Hernandez MJ, R´ios JJ, et al. Sebaceus naevi: a clinicopathologic study. J Eur Acad Dermatol Venereol 2002; 16 (4): 319–24PubMedCrossRefGoogle Scholar
  17. 17.
    Mataix J, Betlloch I, Bañuls J, et al. Umbilicated papules on genitals in two siblings. Actas Dermosifilogr 2006; 97: 609–10CrossRefGoogle Scholar
  18. 18.
    Marrogi AJ, Wick MR, Dehner LP. Benign cutaneous adnexal tumors in childhood and young adults, excluding pilomatrixoma: review of 28 cases and literature. J Cutan Pathol 1991; 18: 20–7PubMedCrossRefGoogle Scholar
  19. 19.
    Gonzalez S, Duarte I. Benign fibrous histiocytoma of the skin: a morphologic study of 290 cases. Pathol Res Pract 1982; 174 (4): 379–91PubMedCrossRefGoogle Scholar
  20. 20.
    Hernandez-Martin A, Baselga E, Drolet BA, et al. Juvenile xanthogranuloma. J Am Acad Dermatol 1997; 36 (3 Pt 1): 355–67PubMedCrossRefGoogle Scholar
  21. 21.
    Requena L, Sangüeza OP. Benign neoplasms with neural differentiation: a review. Am J Dermatopathol 1995; 17 (1): 75–96PubMedCrossRefGoogle Scholar

Copyright information

© Adis Data Information BV 2007

Authors and Affiliations

  • Ana Lucas
    • 1
  • Isabel Betlloch
    • 1
  • Maria Planelles
    • 2
  • Teresa Martínez
    • 3
  • Maria Péerez-Crespo
    • 1
  • Javier Mataix
    • 1
  • Isabel Belinchón
    • 1
  1. 1.Department of DermatologyHospital General Universitario de AlicanteAlicanteSpain
  2. 2.Department of PathologyHospital General Universitario de AlicanteAlicanteSpain
  3. 3.Department of PediatricsHospital General Universitario de AlicanteAlicanteSpain

Personalised recommendations