Drugs in R & D

, Volume 5, Issue 1, pp 46–49 | Cite as

Insulin inhalation

NN 1998
Adis R&D Profile

Keywords

Insulin Analogue Regular Human Insulin Inhalation Technique Reduce Blood Glucose Level Humalog 

References

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    Novo Nordisk, Aradigm Corporation. Novo Nordisk and Aradigm Corporation Announce Initiation of Phase 3 Studies Of AERx Pulmonary Insulin Delivery System (NN1998). Media Release: 3 Sep 2002. Available from URL: http://www.novonordisk.com Google Scholar
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    Farr S, McElduff A, Ward E. A comparison of the pharmacokinetics and pharmacodynamics of inhaled insulin administered as different strength solutions to healthy volunteers. Diabetes 47 (Suppl. 1): 61, May 1998Google Scholar
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    Himmelmann A, Jendle J, Mellén A, et al. The impact of smoking on inhaled insulin. Diabetes Care 26: 677–682, Mar 2003PubMedCrossRefGoogle Scholar
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    Brunner GA, Balent B, Sendlehofer G, et al. Pharmacokinetics and pharmacodynamics of inhaled versus subcutaneous insulin in subjects with type 1 diabetes — a Glucose Clamp Study. Diabetes 49 (Suppl. 1): 76 (plus poster), May 2000Google Scholar
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    Aradigm shows inhaled insulin may allow diabetics to control meal-time glucose levels control over breathing may be key to achieving reproducible delivery of inhaled insulin. PR New-swire [online]: [2 pages], 29 Apr 1997. Available from URL: http://www.newspage.com Google Scholar
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    Aradigm Corporation. Electronic insulin inhaler shows faster reduction of blood glucose than injections. Clinical trials find AERx (Rm) system delivers insulin more rapidly. Media Release: [2 pages], 17 Jun 1998Google Scholar
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    Henry RR, Mudaliar SRD, Howland III WC, et al. Inhaled insulin using the AERx insulin Diabetes Management System in healthy and asthmatic subjects. Diabetes Care 26: 764–769, Mar 2003PubMedCrossRefGoogle Scholar
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    Hermansen K, Rönnemaa T, Petersen AH, et al. Intensive treatment with pulmonary insulin using the AERx (Rm) insulin diabetes management system — a proof of concept trial in type 2 diabetic patients. Diabetes 51 (Suppl. 2): 48, Jun 2002Google Scholar
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    Cramer J, Okikawa J, Clauson P. Compliance with inhaled insulin treatment using AERx(Rm) iDMS insulin diabetes management system. Diabetes 52 (Suppl. 1): 103, Jun 2003Google Scholar

Copyright information

© Adis Data Information BV 2004

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