Drugs in R & D

, Volume 2, Issue 5, pp 315–317 | Cite as


Protovir®, MSL 109, EV2 7, SDZ MSL 109
Section 1: Cytomegalovirus Retiniti Adis R&D Profile


Adis International Limited Ganciclovir Retinitis Foscarnet Undergo Bone Marrow Transplan 
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  1. 1.
    Drobyski WR, Gottlieb M, Carrigan D, et al. Phase I study of safety and pharmacokinetics of a human anticytomegalovirus monoclonal antibody in allogeneic bone marrow transplant recipients. Transplantation 1991 Jun; 51: 1190–6PubMedCrossRefGoogle Scholar
  2. 2.
    Nokta MA, Tolpin MD, Nadler PI, et al. Human monoclonal anti cytomegalovirus antibody (MSL-109): enhancement of in vitro ganciclovir induced inhibition of CMV replication. Antiviral Res 1991 Apr; 15 Suppl. 1: 77Google Scholar
  3. 3.
    Protein Design Labs announces results from phase II study of PROTOVIR (Rm) in bone marrow transplantation. PR Newswire [online]. 2 Jul 1997. URL: [Accessed 1997 Jul 14]
  4. 4.
    Dunkel EC, Siegel ML, Brooks J, et al. MSL-109 therapy of human cytomegalovirus-induced chorioretinitis in the rabbit. Antiviral Res 1991 Apr; 15 Suppl. 1: 121Google Scholar
  5. 5.
    Lakeman F, Blevins C, Whitley R, et al. In vitro neutralization of cytomegalovirus strains by a human monoclonal antibody, MSL-109. Antiviral Res 1991 Apr; 15 Suppl. 1: 77CrossRefGoogle Scholar
  6. 6.
    Nokta M, Tolpin M, Nadler P, et al. Combination effects of a human monoclonal anti cytomegalovirus (CMV) antibody (MSL 109) and foscarnet or ganciclovir on CMV replication in vitro. Antiviral Res 1993; 20 Suppl. 1: 110Google Scholar
  7. 7.
    Tolpin M, Pollard R, Tierney M, et al. Combination therapy of cytomegalovirus retinitis with a human monoclonal anti-CMV antibody (SDZ MSL 109) and either ganciclovir or foscarnet. 9th International Conference on AIDS; 1993 Jun 6–11; Berlin, I: 54Google Scholar
  8. 8.
    Protein Design Labs announces halt to one of three ongoing clinical trials in CMV disease [media release]. PR Newswire 1996 Aug 14Google Scholar

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© Adis International Limited 1999

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