Section 1: Type 2 Diabete Mellitus Adis R&D Profile
KeywordsAdis International Limited Piperazine Imidazoline MIN6 Cell Antidiabetic Activity
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- 1.Wang X, Rondu F, Lamouri A, et al. Effect of S-21663 (PMS 812), an imidazoline derivative, on glucose tolerance and insulin secretion in a rat model of type II diabetes. J Pharmacol Exper Ther 1996 Jul; 278: 82–9Google Scholar
- 2.Rondu F, Le Bihan G, Wang X, et al. Structure-activity relationships in a series of substituted piperazines potentially active in non-insulin-dependent diabetes mellitus [abstract]. XIIIth International Symposium of Medicinal Chemistry. 1994 Sep 19–23; Paris, 263Google Scholar
- 4.Le Bihan G, Rondu F, Pelé-Tounian A, et al. Design and synthesis of imidazoline derivatives active on glucose homeostasis in a rat model of type II diabetes. 2. Syntheses and biological activities of 1,4-dialkyl-, 1,4-dibenzyl, and 1-benzyl- 4-alkyl-2-(4′,5′-dihydro-1′H-imidazol-2′-yl)piperazines and isosteric analogues of imidazoline. J Med Chem 1999 May 6; 42: 1587–603PubMedCrossRefGoogle Scholar
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