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Rapid Protection against Hepatitis A and B Using an Accelerated Vaccination Schedule

Comparison of Combined Vaccine, Twinrix®, with Separate Vaccines

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Table I
Fig. 1

Notes

  1. Tradenames are used for product identification only and do not imply endorsement.

References

  1. Nothdurft HD, Dietrich M, Zuckerman JN, et al. A new accelerated vaccination schedule for rapid protection against hepatitis A and B. Vaccine 2002; 20(7-8): 1157–62

    Article  PubMed  CAS  Google Scholar 

  2. Löscher T, Keystone JS, Steffen R. Vaccination of travellers against hepatitis A and B. J Travel Med 1999; 6: 107–14

    Article  PubMed  Google Scholar 

  3. Van Damme P, Cramm M, Van Gompel A, et al. Analysis of travellers profile in Belgium [abstract 371]. Proceedings of the 3rd Conference on International Travel Medicine; 1993 Apr 25–29; Paris, France: 267

  4. Bruguera M, Bayas JM, Vilella A, et al. Immunogenicity and reactogenicity of a combined hepatitis A and B vaccine in young adults. Vaccine 1996; 14(15): 1407–11

    Article  PubMed  CAS  Google Scholar 

  5. Leroux-Roels G, Moreau E, Desombre I, et al. Safety and immunogenicity of a combined hepatitis A and B vaccine in young healthy adults. Scand J Gastroenterol 1996; 31: 1027–31

    Article  PubMed  CAS  Google Scholar 

  6. Ruetter J, Bart PA, Francioli P, et al. Production of antibody to hepatitis A virus and hepatitis B surface antigen measured after combined hepatitisA/hepatitis B vaccination in 242 adult volunteers. J Viral Hepat 1998; 5(3): 205–11

    Article  Google Scholar 

  7. Thompson SC, Norris M. Immunogenicity and reactogenicity of a combined hepatitis A and B vaccine in adolescents. Int J Infect Dis 1998; 2: 193–6

    Article  PubMed  CAS  Google Scholar 

  8. Van Damme P, Lievens M, Stoffel M, et al. Rapid seroconversion rates after first dose of an inactivated hepatitis A vaccine (Havrix 1440™) [abstract]: results of a retrospective analysis. In: Travel & Epidemics. 3rd European Conference on Travel Medicine; 2002 May 15–18; Florence, Italy: 210

  9. Iwarson S, Lindh M, Widerström L. Excellent booster response 4–6 y after a single primary dose of an inactivated hepatitis A vaccine. Scand J Infect Dis 2002; 34: 110–1

    Article  PubMed  Google Scholar 

  10. Bock HL, Loscher T, Scheiermann N, et al. Accelerated schedule for Hepatitis B immunization. J Travel Med 1995; 2: 213–7

    Article  PubMed  Google Scholar 

  11. Thoelen S, Van Damme P, Leentvaar-Kuypers A, et al. The first combined vaccine against hepatitis A and B: an overview. Vaccine 1999; 17(13-14): 1657–62

    Article  PubMed  CAS  Google Scholar 

  12. Bock HL, Kruppenbacher JP, Bienzle U, et al. Does the concurrent administration of an inactivated hepatitis A vaccine influence the immune response to other travelers vaccines? J Travel Med 2000; 7: 74–8

    Article  PubMed  CAS  Google Scholar 

  13. Joines RW, Blatter M, Abraham B, et al. A prospective, randomized, comparative US trial of a combination hepatitis A and B vaccine (Twinrix) with corresponding monovalent vaccines (Havrix and Engerix-B) in adults. Vaccine 2001; 19: 4710–9

    Article  PubMed  CAS  Google Scholar 

  14. Wagstaff AJ, Balfour JA. Combination hepatitis A and B vaccine. BioDrugs 1997; 8: 235–9

    Article  PubMed  CAS  Google Scholar 

  15. Burgess MA, Rodger AJ, Waite SA, et al. Comparative immunogenicity and safety of two dosing schedules of a combined hepatitis A and B vaccine in healthy adolescent volunteers: an open, randomised study. Vaccine 2001; 19: 4835–41

    Article  PubMed  CAS  Google Scholar 

  16. Van Der Wielen M, Van Damme P, Collard F. A two dose schedule for combined hepatitis A and hepatitis B vaccination in children ages one to eleven years. Pediatr Infect Dis J 2000; 19: 848–53

    Article  Google Scholar 

  17. Ramonet M, da Silveira TR, Lisker-Melman M, et al. A two-dose combined vaccine against hepatitis A and hepatitis B in healthy children and adolescents compared to the corresponding monovalent vaccines. Arch Med Res 2002; 33: 67–73

    Article  PubMed  Google Scholar 

  18. Bosnak M, Dikici B, Bosnak V, et al. Accelerated hepatitis B vaccination schedule in childhood. Pediatr Int 2002; 44: 663–5

    Article  PubMed  Google Scholar 

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Acknowledgements

The authors have provided no information on sources of funding or on conflicts of interest directly relevant to the content of this short communication.

Author information

Authors and Affiliations

  1. Department of Infectious Diseases and Tropical Medicine, Ludwig-Maximilians University, Leopoldstr. 5, Munich, D-80802, Germany

    Hans D. Nothdurft MD

  2. Department of Medicine, Bernhard-Nocht Institute for Tropical Medicine, Hamburg, Germany

    Manfred Dietrich

  3. Royal Free and University College Medical School, University College London, London, UK

    Jane N. Zuckerman

  4. Institute of Tropical Medicine, University Hospital, Tübingen, Germany

    Jürgen Knobloch

  5. University Hospital and Medical Center, Ulm, Germany

    Peter Kern

  6. GlaxoSmithKline GmbH & Co. KG, Munich, Germany

    Roland Sänger

Authors
  1. Hans D. Nothdurft MD
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  2. Manfred Dietrich
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  3. Jane N. Zuckerman
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  4. Jürgen Knobloch
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  5. Peter Kern
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  6. Roland Sänger
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Corresponding author

Correspondence to Hans D. Nothdurft MD.

Additional information

The study data in this Short Communication have been presented in full in Vaccine, Vol. 20. Nothdurft HD, Dietrich M, Zuckerman JN, et al. A new accelerated vaccination schedule for rapid protection against hepatitis A and B, pp. 1157-62. [1] Copyright 2002. This article is published with permission from Elsevier Science. The discussion has been updated

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Nothdurft, H.D., Dietrich, M., Zuckerman, J.N. et al. Rapid Protection against Hepatitis A and B Using an Accelerated Vaccination Schedule. BioDrugs 17 (Suppl 1), 15–18 (2003). https://doi.org/10.2165/00063030-200317001-00004

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  • DOI: https://doi.org/10.2165/00063030-200317001-00004

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