Clinical Drug Investigation

, Volume 29, Issue 3, pp 153–159 | Cite as

User Satisfaction with the Combined Oral Contraceptive Drospirenone 3 mg/Ethinylestradiol 20 μg (Yasminelle®) in Clinical Practice

A Multi-Country, Questionnaire-Based Study
Original Research Article

Abstract

Objective: To assess women’s perception of a combined oral contraceptive (COC) containing drospirenone 3 mg/ethinylestradiol (EE) 20 μg administered in the conventional 21/7 regimen (drospirenone 3mg/EE 20 μg 21/7 regimen [Yasminelle®]) in clinical practice.

Methods: This questionnaire-based study was performed in 12 European countries and included women who had been taking the drospirenone 3 mg/EE 20 μg 21/7 regimen COC for ≥3 months.

Results: Of 16 461 completed questionnaires, 12 277 were from women who had been using the drospirenone 3 mg/EE 20 μg 21/7 regimen COC for ≥3 months — 34% of women were new users of COCs and 65% had switched from alternative contraceptive brands. The mean age of these respondents was approximately 27 years. Seventy percent of women who indicated that they had skin problems before taking the drospirenone 3 mg/EE 20 μg 21/7 regimen COC responded that their skin had improved with treatment (3030/4305). Sixty-nine percent of women who had switched to the drospirenone 3 mg/EE 20 μg 21/7 regimen COC because of weight problems with their previous method of contraception responded that they had experienced weight loss (1205/1745). Approximately 95% of respondents said they were satisfied with the drospirenone 3 mg/EE 20 μg 21/7 regimen COC. Moreover, 83% of respondents said they would recommend this COC to a friend.

Conclusion: There were high levels of perceived satisfaction with the drospirenone 3 mg/EE 20 μg 21/7 regimen COC. The reported effects on weight loss (due to decreased water retention) and skin problems are consistent with the antimineralocorticoid and antiandrogenic benefits of drospirenone-containing COCs.

Keywords

Acne Combine Oral Contraceptive Premenstrual Symptom Weight Problem Drospirenone 

Notes

Acknowledgements

Bayer Schering Pharma AG, Berlin, Germany provided funding for this study and were involved in conducting the analysis and also reviewing the manuscript. The author would like to acknowledge Anne Zimmermann for her conduct and analysis of the study, and Richard Glover for his editorial assistance with the development of this manuscript, with the financial support of Bayer Schering Pharma AG. The author has received an honorarium from Bayer Schering Pharma AG for presentation of the content of this study at a conference.

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Copyright information

© Adis Data Information BV 2009

Authors and Affiliations

  1. 1.Rock Court Medical CentreBlackrockIreland

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