Summary
The aim of this controlled, randomised, crossover study was to evaluate the patient acceptability of 2 different nicotine chewing gum brands on the Danish market, Nicotinell® (Ciba-Geigy) and Nicorette® (Pharmacia Upjohn). 20 healthy smokers tested one brand in one week and the next week were crossed over to the alternative product. From scores on a 10cm visual analogue scale (VAS) combined with descriptive words it was shown that taste, texture and stickiness were significantly (p < 0.0001, p < 0.0003, and p < 0.005, respectively) better accepted over time for Nicotinell® than for Nicorette®. At the end of the 2-week study period, the participants were asked to give their preference and 90% of the subjects preferred Nicotinell® to Nicorette®.
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Rasmussen, M., Jørgensen, J.T. & Rømsing, J. Patient Acceptability of Two Different Brands of Nicotine Chewing Gum. Clin. Drug Invest. 13, 277–281 (1997). https://doi.org/10.2165/00044011-199713050-00007
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DOI: https://doi.org/10.2165/00044011-199713050-00007