Clinical Drug Investigation

, Volume 13, Issue 5, pp 277–281 | Cite as

Patient Acceptability of Two Different Brands of Nicotine Chewing Gum

  • M. Rasmussen
  • J. T. Jørgensen
  • J. Rømsing
Outcomes Research


The aim of this controlled, randomised, crossover study was to evaluate the patient acceptability of 2 different nicotine chewing gum brands on the Danish market, Nicotinell® (Ciba-Geigy) and Nicorette® (Pharmacia Upjohn). 20 healthy smokers tested one brand in one week and the next week were crossed over to the alternative product. From scores on a 10cm visual analogue scale (VAS) combined with descriptive words it was shown that taste, texture and stickiness were significantly (p < 0.0001, p < 0.0003, and p < 0.005, respectively) better accepted over time for Nicotinell® than for Nicorette®. At the end of the 2-week study period, the participants were asked to give their preference and 90% of the subjects preferred Nicotinell® to Nicorette®.


Nicotine Visual Analogue Scale Score Drug Invest Nicotine Addiction Patient Acceptability 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Adis International Limited 1997

Authors and Affiliations

  • M. Rasmussen
    • 1
  • J. T. Jørgensen
    • 2
  • J. Rømsing
    • 1
  1. 1.Department of PharmaceuticsThe Royal Danish School of PharmacyCopenhagenDenmark
  2. 2.Ciba-Geigy LtdCopenhagenDenmark

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