Skip to main content
Log in

Clarithromycin-Oral Anticoagulants Interaction: Report of Five Cases

  • Case Report
  • Published:
Clinical Drug Investigation Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Kirst HA. New macrolides: expanded horizons for an old class of antibiotic. J Antimicrob Chemother 1991; 28: 787–90

    Article  PubMed  CAS  Google Scholar 

  2. Rosenstiel NA, Adam D. Macrolide antibacterials. Drug interactions of clinical significance. Drug Saf 1995; 13: 105–22

    Article  Google Scholar 

  3. Amsden GW. Macrolides versus azalides: a drug interaction update. Ann Pharmacother 1995; 29: 906–17

    PubMed  CAS  Google Scholar 

  4. Logan RPH, Bardhan KD, Celestin LR. Eradication of Helicobacter pylori and prevention of recurrence of duodenal ulcer: a randomized, double-blind, multi-center trial of omeprazole with or without clarithromycin. Aliment Pharmacol Ther 1995; 9: 417–24

    Article  PubMed  CAS  Google Scholar 

  5. Pierce M, Crampton S, Henry D, et al. A randomized trial of clarithromycin as prophylaxis against disseminated Mycobacterium avium complex infection in patients with advanced acquired immunodeficiency syndrome. N Engl J Med 1996; 335: 384–91

    Article  PubMed  CAS  Google Scholar 

  6. Abbott Laboratories. Clarithromycin (Biaxin®). Package insert. 1995; North Chicago, IL, USA

  7. Albani F, Riva R, Baruzzi A. Clarithromycin-carbamazepine interaction: a case report. Epilepsia 1993; 34: 161–2

    Article  PubMed  CAS  Google Scholar 

  8. Honig PK, Wortham DC, Zamani K, et al. Comparison of the effect of the macrolide antibiotics erythromycin, clarithromycin and azithromycin on terfenadine steady-state pharmacokinetic and electrocardiographic parameters. Drug Invest 1994; 7: 148–56

    CAS  Google Scholar 

  9. Pollak PT, Sketris IS, MacKenzie SL, et al. Delirium probably induced by clarithromycin in a patient receiving fluoxetine. Ann Pharmacother 1995; 29: 486–8

    PubMed  CAS  Google Scholar 

  10. Ferrari SL, Goffin E, Mourad M, et al. The interaction between clarithromycin and cyclosporine in kidney transplant recipients. Transplantation 1994; 58: 725–7

    PubMed  CAS  Google Scholar 

  11. Weibert RT, Lorentz SM, Townsend RJ, et al. Effect of erythromycin in patients receiving long-term warfarin therapy. Clin Pharm 1989; 8: 210–4

    PubMed  CAS  Google Scholar 

  12. Paulsen O, Nilsson LG, Saint-Salvi B, et al. No effect of roxithromycin on pharmacokinetic or pharmacodynamic properties of warfarin and its enantiomers. Pharmacol Toxicol 1988; 63: 215–20

    Article  PubMed  CAS  Google Scholar 

  13. Gillum JG, Israel DS, Polk RE. Pharmacokinetic drug interactions with antimicrobial agents. Clin Pharmacokinet 1993; 25: 450–82

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sánchez, B., Muruzábal, M.J., Peralta, G. et al. Clarithromycin-Oral Anticoagulants Interaction: Report of Five Cases. Clinical Drug Investigation 13, 220–222 (1997). https://doi.org/10.2165/00044011-199713040-00007

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00044011-199713040-00007

Keywords

Navigation