Advertisement

Drugs & Therapy Perspectives

, Volume 19, Issue 7, pp 4–6 | Cite as

Imatinib Mesylate in GIST: profile report

  • Ian Judson
  • Allan van Oosterom
Drugs and Profile Reports
  • 18 Downloads

Keywords

Imatinib Chronic Myeloid Leukaemia Imatinib Mesylate Metastatic Gist Dermatofibrosarcoma Protuberans 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Croom KF, Perry CM. Imatinib mesylate: in the treatment of gastrointestinal stromal tumours. Drugs 2003; 63(5): 513–22PubMedCrossRefGoogle Scholar
  2. 2.
    Judson I. Imatinib mesylate: a viewpoint by Ian Judson. Drugs 2003; 63(5): 523CrossRefGoogle Scholar
  3. 3.
    Van Oosterom A. Imatinib mesylate: a viewpoint by Allan van Oosterom. Drugs 2003; 63(5): 523–4CrossRefGoogle Scholar
  4. 4.
    Lyseng-Williamson K, Jarvis B. Imatinib. Drugs 2001; 61(12): 1765–74; discussion 1775–6PubMedCrossRefGoogle Scholar
  5. 5.
    Buchdunger E, Cioffi CL, Law N, et al. Abl protein-tyrosine kinase inhibitor ST1571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors. J Pharmacol Exp Ther 2000; 295(1): 139–45PubMedGoogle Scholar
  6. 6.
    Druker BJ, Tamura S, Buchdunger E, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 1996 May; 2: 561–6PubMedCrossRefGoogle Scholar
  7. 7.
    Demetri GD, von Mehren M, Blanke CD, et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 2002 Aug 15; 347(7): 472–80PubMedCrossRefGoogle Scholar
  8. 8.
    van Oosterom AT, Judson IR, Verweij J, et al. Update of phase I study of imatinib (STI571) in advanced soft tissue sarcomas and gastrointestinal stromal tumours: a report of the EORTC soft tissue and bone sarcoma group. Eur J Cancer 2002; 38 Suppl. 5: S83–7PubMedCrossRefGoogle Scholar
  9. 9.
    van Oosterom AT, Judson I, Verweij J, et al. Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study. Lancet 2001 Oct 27; 358(9291): 1421–3PubMedCrossRefGoogle Scholar

Copyright information

© Adis Data Information BV 2003

Authors and Affiliations

  • Ian Judson
    • 1
  • Allan van Oosterom
    • 2
  1. 1.Sarcoma UnitRoyal Marsden HospitalLondonUK
  2. 2.Department of Clinical OncologyLeuven University HospitalLeuvenBelgium

Personalised recommendations