Drugs & Therapy Perspectives

, Volume 12, Issue 6, pp 14–16 | Cite as

HRT increases likelihood of venous thromboembolism, but overall risk small

Drug Reactions and Interactions
  • 9 Downloads

Keywords

Adis International Limited Anxiety Disorder Hormone Replacement Therapy Generalize Anxiety Disorder Venous Thromboembolism 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Committee on Safety of Medicines, Medicines Control Agency. Risk of venous thromboembolism with hormone replacement therapy. Curr Probl Pharmacovigilance 1996; 22: 9–10Google Scholar
  2. 2.
    Castellsague J, Pérez Gutthann S, García Rodríguez LA. Recent epidemiological studies of the association between hormone replacement therapy and venous thromboembolism: a review. Drug Saf 1998 Feb; 18(2): 117–23PubMedCrossRefGoogle Scholar
  3. 3.
    A report from the Boston Collaborative Drug Surveillance Program, Boston University Medical Center. Surgically confirmed gallbladder, venous thromboembolism, and breast tumors in relation to postmenopausal estrogen therapy. N Engl J Med 1974; 290: 15–9CrossRefGoogle Scholar
  4. 4.
    Daly E, Vessey MP, Hawkins MM, et al. Case-control study of venous thromboembolism disease and use of hormone replacement therapy. Lancet 1996; 348: 977–80PubMedCrossRefGoogle Scholar
  5. 5.
    Jick H, Derby L. The risk of hospitalization for idiopathic venous thromboembolism among users of postmenopausal estrogens. Lancet 1996; 348: 981–3PubMedCrossRefGoogle Scholar
  6. 6.
    Pérez-Gutthann S, García-Rodríguez LA, Castellsague J, et al. Hormone replacement therapy and risk of venous thromboembolism: population based case-control study. BMJ 1997; 314: 796–800PubMedCrossRefGoogle Scholar
  7. 7.
    Varas C, García-Rodríguez LA, Cattaruzzi C, et al. Hormone replacement therapy and the risk of hospitalization for venous thromboembolism: a population-based study in southern Europe. Am J Epidemiol 1998 Feb 15; 147(4): 387–90CrossRefGoogle Scholar
  8. 8.
    Grodstein F, Stampfer MJ, Goldhaber SZ, et al. Prospective study of exogenous hormones and risk of pulmonary embolism in women. Lancet 1996; 348: 983–7PubMedCrossRefGoogle Scholar
  9. 9.
    Vandenbroucke JP, Koster T, Briet E, et al. Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation. Lancet 1994; 344: 1454–7CrossRefGoogle Scholar

Copyright information

© Adis International Limited 1998

Personalised recommendations