Drugs & Therapy Perspectives

, Volume 8, Issue 8, pp 1–6 | Cite as

Lamivudine and stavudine: useful additions to the available nucleoside analogues

New Drugs and Therapeutic

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Lea AP, Faulds D. Stavudine: a review of its pharmacodynamic and pharmacokinetic properties and clinical potential in HIV infection. Drugs 1996 May; 51: 846–64PubMedCrossRefGoogle Scholar
  2. 2.
    Moyle G. Activity and role of lamivudine in the treatment of adults with human immunodeficiency virus type 1 infection: a review. Expert Opin Invest Drugs 1996 Aug; 5: 913–24CrossRefGoogle Scholar
  3. 3.
    Styrt BA, Piazza-Hepp TD, Chikami GK. Clinical toxicity of antiretroviral nucleoside analogs. Antiviral Res 1996 Jul; 31: 121–35PubMedCrossRefGoogle Scholar
  4. 4.
    British National Formulary No. 31. London: The Pharmaceutical Press, 1996 Mar: 266–8Google Scholar
  5. 5.
    Epivir tablets and solution [prescribing information]. Pharm J 1996 Aug 17; 257: 227Google Scholar
  6. 6.
    Zerit capsules [prescribing information]. Pharm J 1996 Aug 24; 257: 257Google Scholar
  7. 7.
    1995 Physicians GenRx. St Louis, Missouri: Mosby-Year Book, Inc., 1995Google Scholar
  8. 8.
    Gao W-Y, Agbaria R, Driscoll JS, et al. Divergent anti-human immunodeficiency virus activity and anabolic phosphorylation of 2′,3′-dideoxynucleoside analogs in resting and activated human cells. J Biol Chem 1994 Apr 29; 269: 12633–8PubMedGoogle Scholar
  9. 9.
    Merrill DP, Moonis M, Chou T-C, et al. Lamivudine or stavudine in two-and three-drug combinations against human immunodeficiency virus type 1 replication in vitro. J Infect Dis 1996 Feb; 173: 355–64PubMedCrossRefGoogle Scholar
  10. 10.
    Katlama C, Ingrand D, Loveday C, et al. Safety and efficacy of lamivudine-zidovudine combination therapy in antiretroviral-naive patients: a randomized controlled comparison with zidovudine monotherapy. JAMA 1996 Jul 10; 276: 118–25PubMedCrossRefGoogle Scholar
  11. 11.
    Carpenter CCJ, Fischl MA, Hammer SM, et al. Antiretroviral therapy for HIV infection in 1996: recommendations of an international panel. JAMA 1996 Jul 10; 276: 146–54PubMedCrossRefGoogle Scholar
  12. 12.
    Eron JJ, Benoit SL, Jemsek J. Treatment with lamivudine, zidovudine, or both in HIV-positive patients with 200 to 500 CD4;pl cells per cubic millimeter. N Engl J Med 1995 Dec 21; 333: 1662–9PubMedCrossRefGoogle Scholar
  13. 13.
    Pavia AT, Gathe J, BMS-019 Studv Group Investigators, et al. Clinical efficacy of stavudine (d4T, Zerit®) compared to zidovudine (ZDV, Retrovir®) in ZDV-pretreated HIV positive patients [abstract]. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy; 1995;235Google Scholar
  14. 14.
    Gottlieb M, Peterson D, Adler M, et al. Comparison of safety and efficacy of two doses of stavudine (Zerit, d4T) in a large simple trial in the US Parallel Track Program [abstract]. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy; 1995; 235Google Scholar
  15. 15.
    Bartlett JA, Benoit SL, Johnson VA. Lamivudine plus zidovudine compared with zalcitabine plus zidovudine in patients with HIV infection: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 1996 Aug 1; 125: 161–72PubMedGoogle Scholar
  16. 16.
    Staszewski S, Loveday C, Picazo JJ, et al. Safety and efficacy of lamivudine-zidovudine combination therapy in zidovudine-experienced patients: a randomized controlled comparison with zidovudine monotherapy. JAMA 1996 Jul 10; 276: 111–7PubMedCrossRefGoogle Scholar
  17. 17.
    Mars ME, Gensollen S, Ravaux L, et al. Association between AZT and d4T in HIV infected patients: a pilot study (comparison with d4T, AZT, and AZT + ddI) [abstract]. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy; 1995; 226Google Scholar
  18. 18.
    McGinley L. States move to ration promising AIDS drugs. Wall Street Journal 1996 Aug 22: B1Google Scholar

Copyright information

© Adis lnternational Limited 1996

Personalised recommendations