Drugs & Therapy Perspectives

, Volume 6, Issue 4, pp 12–14 | Cite as

Universal neonatal vitamin K supplementation still recommended

New Drugs and Therapeutic


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Vitamin K Ad Hoc Task Force. Controversies concerning vitamin K and the newborn. Pediatrics 1993 May; 91(5): 1001–3Google Scholar
  2. 2.
    von Kries R, Hanawa Y. Neonatal vitamin K prophylaxis: report of Scientific and Standardization Subcommittee on Perinatal Haemostasis. Thromb Haemost 1993; 69(3): 293–5Google Scholar
  3. 3.
    Golding J, Paterson M, Kinlen LJ. Factors associated with childhood cancer in a national cohort study. Br J Cancer 1990; 62: 304–8PubMedCrossRefGoogle Scholar
  4. 4.
    Golding J, Greenwood R, Birmingham K, et al. Childhood cancer, intramuscular vitamin K1 and pethidine given during labour. BMJ 1992 Aug 8; 305: 341–6PubMedCrossRefGoogle Scholar
  5. 5.
    National Health and Medical Research Council, Australian College of Paediatrics, Royal Australasian College of Obstetricians and Gynaecologists. Joint statement and recommendations: vitamin K prophylaxis for haemorrhagic disease in infancy. 1994 Mar 9: 1–2Google Scholar
  6. 6.
    Thorp JA, Gaston L, Caspers DR, et al. Current concepts and controversies in the use of vitamin K. Drugs 1995 Mar; 49(3): 376–87PubMedCrossRefGoogle Scholar
  7. 7.
    McNinch AW, Tripp JH. Haemorrhagic disease of the newborn in the British Isles: two year prospective study. BMJ 1991 Nov 2; 303: 1105–9PubMedCrossRefGoogle Scholar
  8. 8.
    von Kries R, Hachmeister A, Göbel U. Repeated oral vitamin K prophylaxis in West Germany: acceptance and efficacy. BMJ 1995 Apr 29; 1097–8Google Scholar
  9. 9.
    Olsen JH, Hertz H, Blinkenberg K, et al. Vitamin K regimens and incidence of childhood cancer in Denmark. BMJ 1994 Apr 2; 308: 895–6PubMedCrossRefGoogle Scholar
  10. 10.
    Ekelund H, Finnström O, Gunnarskog J, et al. Administration of vitamin K to newborn infants and childhood cancer. BMJ 1993; Jul 10; 307: 889–91CrossRefGoogle Scholar
  11. 11.
    Klebanoff MA, Read JS, Mills JL, et al. The risk of childhood cancer after neonatal exposure to vitamin K. N Engl J Med 1993 Sep 23; 329(13): 905–8PubMedCrossRefGoogle Scholar
  12. 12.
    Slattery JM. Why we need a clinical trial for vitamin K. BMJ 1994 Apr 2; 308: 908–10PubMedCrossRefGoogle Scholar
  13. 13.
    Draper G, McNinch A. Vitamin K for neonates: the controversy. BMJ 1994 Apr 2; 308: 867–8PubMedCrossRefGoogle Scholar
  14. 14.
    Anai T, Hirota Y, Yoshimatsu J, et al. Can prenatal vitamin K1 (phylloquinone) supplementation replace prophylaxis at birth? Obstet Gynecol 1993; 81: 251–4PubMedGoogle Scholar
  15. 15.
    Greer FR, Marshall S, Suttie JW. Maternal vitamin K1 supplements — effects on human milk concentrations and intakes in breast feeding infants [abstract]. Pediatr Res 1994 Apr; 35 Pt 2; 312AGoogle Scholar
  16. 16.
    Cornelissen M, Steegers-Theunissen R, Kollée L, et al. Supplementation of vitamin K in pregnant women receiving anticonvulsant therapy prevents neonatal vitamin K deficiency. Am J Obstet Gynecol 1993 Mar; 168 Pt1; 884–8PubMedGoogle Scholar
  17. 17.
    Moslet U, Hansen ES. A review of vitamin K, epilepsy and pregnancy. Acta Neurol Scand 1992 Jan; 85: 39–43PubMedCrossRefGoogle Scholar
  18. 18.
    Thorp JA, Parriott J, Ferrette-Smith D, et al. Antepartum vitamin K and phenobarbital for preventing intraventricular hemorrhage in the premature newborn: a randomized, double-blind, placebo-controlled trial. Obstet Gynecol 1994 Jan; 83: 70–6PubMedGoogle Scholar

Copyright information

© Adis International Limited 1995

Personalised recommendations