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Surgical Management of Obesity

A Review of Their Effects on Glucose Metabolism and Insulin Resistance

  • Review Article
  • Published:
Treatments in Endocrinology

Abstract

Obesity continues to plague our society in epidemic proportions. Surgery for morbid obesity is considered by many as the most effective therapy for this complex disorder. Today, multiple surgical procedures for the treatment of obesity are available. As with most procedures, there are benefits and risks associated with open and laparoscopic gastric bypass surgery, as well as with laparoscopic adjustable gastric banding and partial biliopancreatic bypass with a duodenal switch. The risks and complications associated with bariatric surgery may be serious and in some cases life threatening. However, surgery for obesity has shown remarkable results in helping patients to achieve significant long-term weight control. In addition, it is associated with improvement and often resolution of co-morbid conditions, including type 2 diabetes mellitus, systemic hypertension, obesity hypoventilation, sleep apnea, venous stasis disease, pseudotumor cerebri, polycystic ovary syndrome, complications of pregnancy and delivery, gastroesophageal reflux disease, stress urinary incontinence, degenerative joint disease, and non-alcoholic steatohepatitis.

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Acknowledgments

The authors gratefully acknowledge the assistance of Angela Kuhn in manuscript preparation. Dr Sugerman is on the Ethicon Endosurgery, Surgery Advisory Board and has been funded for speaking engagements by US Surgical Corporation. He is the President of the American Society for Bariatric Surgery and Editor in Chief of its new journal Surgery for Obesity and Related Diseases, both of which provide salary support. He is retired from the clinical practice of surgery. Dr Kothari receives fellowship support from US Surgical Corporation.

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  1. Department of General and Vascular Surgery, Gundersen Lutheran Medical Center, 1900 South Avenue, LaCrosse, Wisconsin, 54601, USA

    Michael D. Lara &  Shanu N. Kothari

  2. Division of General/Trauma Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, USA

    Harvey J. Sugerman

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  1. Michael D. Lara
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  2. Shanu N. Kothari
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  3. Harvey J. Sugerman
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Correspondence to Shanu N. Kothari.

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Lara, M.D., Kothari, S.N. & Sugerman, H.J. Surgical Management of Obesity. Mol Diag Ther 4, 55–64 (2005). https://doi.org/10.2165/00024677-200504010-00006

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