CNS Drugs

, Volume 22, Issue 3, pp 257–258 | Cite as

Applying Long-Acting Injectable Antipsychotics in First-Episode Schizophrenia to Achieve First Remission



Risperidone Olanzapine Decanoate Biperiden Persecutive Delusion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Dr Liu has received honoraria from Astra-Zeneca, Eli Lilly, Janssen-Cilag and Otsuka for lectures on the topic of “early identification and treatment of schizophrenia”. Drs Chiang and Wu have no conflicts of interest to declare.


  1. 1.
    Bai YM, Ting Chen T, Chen JY, et al. Equivalent switching dose from oral risperidone to risperidone long-acting injection: a 48-week randomized, prospective, single-blind pharmaco-kinetic study. J Clin Psychiatry 2007; 68(8): 1218–25PubMedCrossRefGoogle Scholar
  2. 2.
    Shi L, Ascher-Svanum H, Zhu B, et al. Characteristics and use patterns of patients taking first-generation depot antipsychotics or oral antipsychotics for schizophrenia. Psychiatr Serv 2007; 58(4): 482–8PubMedCrossRefGoogle Scholar
  3. 3.
    Patel MX, Nikolaou V, David AS. Psychiatrists’ attitudes to maintenance medication for patients with schizophrenia. Psychol Med 2003; 33(1): 83–9PubMedCrossRefGoogle Scholar
  4. 4.
    Chue P, Emsley R. Long-acting formulations of atypical antipsychotics: time to reconsider when to introduce depot antipsychotics. CNS Drugs 2007; 21(6): 441–8PubMedCrossRefGoogle Scholar
  5. 5.
    Emsley R, Rabinowitz J, Medori R. Time course for anti-psychotic treatment response in first-episode schizophrenia. Am J Psychiatry 2006; 163(4): 743–5PubMedCrossRefGoogle Scholar
  6. 6.
    Liu-Scifert H, Houston JP, Adams DH, et al. Association of acute symptoms and compliance attitude in noncompliant patients with schizophrenia. J Clin Psychopharmacol 2007; 27(4): 392–4CrossRefGoogle Scholar
  7. 7.
    Walburn J, Gray R, Gournay K, et al. Systematic review of patient and nurse attitudes to depot antipsychotic medication. Br J Psychiatry 2001; 179: 300–7PubMedCrossRefGoogle Scholar
  8. 8.
    Wunderink L, Nienhuis FJ, Sytema S, et al. Guided discontinuation versus maintenance treatment in remitted first-episode psychosis: relapse rates and functional outcome. J Clin Psychiatry 2007; 68(5): 654–61PubMedCrossRefGoogle Scholar

Copyright information

© Adis Data Information BV 2008

Authors and Affiliations

  1. 1.Department of PsychiatryNational Taiwan University HospitalTaipeiTaiwan

Personalised recommendations