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CNS Drugs

, Volume 8, Issue 3, pp 199–202 | Cite as

Is Once Weekly Administration of Antidepressants Feasible?

Experience with Fluoxetine
  • William J. Burke
  • Shelton E. Hendricks
  • Delores McArthur-Campbell
Current Opinion
  • 28 Downloads

Summary

Antidepressant medications are taken daily or more frequently based on both tradition and pharmacokinetics of the drugs. However, weekly administration may be a feasible option for drugs with a long elimination half-life and flat dose-response curve. In addition to providing effective control of symptoms, it is possible that weekly administration could also benefit patients by reducing costs and minimising drug interactions and adverse effects. The selective serotonin (5-hydroxytryptamine: 5-HT) reuptake inhibitor fluoxetine appears to be a candidate for once weekly administration.

Keywords

Fluoxetine Weekly Administration Recurrent Depression Fluoxetine Treatment Nebraska Medical 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Adis International Limited 1997

Authors and Affiliations

  • William J. Burke
    • 1
  • Shelton E. Hendricks
    • 1
  • Delores McArthur-Campbell
    • 1
  1. 1.Psychopharmacology Research Center, Creighton-Nebraska Department of Psychiatry, University of Nebraska Medical CenterOmahaUSA

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