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Sports Medicine

, Volume 32, Issue 5, pp 297–307 | Cite as

Blood Lipids and Lipoproteins in Child and Adolescent Athletes

Leading Article

Abstract

The purpose of this review is to describe the age- and gender-associated variation in blood lipids of young athletes and examine the association between training status, peak oxygen consumption (.VO 2peak), and body fatness with blood lipids in young athletes. Results from cross-sectional studies suggest similar levels of total cholesterol (TC), lower levels of triglycerides (TG) and low-density lipoprotein-cholesterol (LDL-C), and higher levels of high-density lipoprotein cholesterol (HDL-C) in young athletes compared with controls. Longitudinal data show that the age- and gender-associated variation in blood lipids in young distance runners is similar to youth in the general population; TC and LDL-C remain stable, HDL-C declines during adolescence (especially in males), and TG increases with age. Considerable heterogeneity exists in the blood lipids of young athletes, including dyslipidaemic values. Age, sexual maturity status, training status, VO 2peak and body fatness are determinants of blood lipids in young athletes. VO 2peak is a significant predictor of HDL-C independent of body fatness. Further research iswarranted to examine: (i) the prevalence rates of dyslipidaemia in various sport groups; and (ii) the complex interactions of genes, biological maturation, exercise training, dietary intake and composition, skeletal muscle and adipose tissue properties on lipoprotein metabolism in young athletes.

Keywords

Exercise Training Blood Lipid Training Status Subcutaneous Adipose Tissue Distance Runner 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgements

The author has no conflicts of interest.

References

  1. 1.
    Tamir I, Heiss G, Glueck CJ, et al. Lipid and lipoprotein distributions in White children ages 6–19 yr: the Lipid Research Clinics Program Prevalence Study. J Chronic Dis 1981; 34: 27–39PubMedCrossRefGoogle Scholar
  2. 2.
    Valimaki I, Hursti M-L, Pihlakoski L, et al. Exercise performance and serum lipids in relation to physical activity in schoolchildren. Int J Sports Med 1980; 1: 132–6CrossRefGoogle Scholar
  3. 3.
    Nizankowska-Blaz T, Abramowicz T. Effects of intensive physical training on serum lipids and lipoproteins. Acta Paediatr Scand 1983; 72: 357–9PubMedCrossRefGoogle Scholar
  4. 4.
    Smith BW, Metheny WP, Van Huss WD, et al. Serum lipids and lipoprotein profiles in elite age-group endurance runners [abstract]. Circulation 1983; 68: 111–191Google Scholar
  5. 5.
    Smith BW, Sparrow AW, Heusner WW, et al. Serum lipid profiles of pre-teenage swimmers [abstract]. Med Sci Sports Exerc 1985; 17: 220Google Scholar
  6. 6.
    Atomi Y, Kuroda Y, Asami T, et al. HDL-cholesterol of children (10 to 12 years of age) related to.VO2max, body fat, and sex. In: Rutenfranz J, Mocellin R, Klimt F, editors. Children and exercise: XII. Champaign (IL): Human Kinetics, 1986: 167–72Google Scholar
  7. 7.
    Macek M, Bell D, Rutenfranz J, et al. A comparison of coronary risk factors in groups of trained and untrained adolescents. Eur J Appl Physiol 1989; 58: 577–82CrossRefGoogle Scholar
  8. 8.
    Kyle JM, Walker RB, Riales RR, et al. Student athletes cholesterol screening during routine precompetition examination. J Fam Pract 1991; 33: 172–6PubMedGoogle Scholar
  9. 9.
    Eisenmann JC, Womack CJ, Reeves MJ, et al. Blood lipids of young distance runners: distribution and inter-relationships among training volume, peak oxygen consumption, and body fatness. Eur J Appl Physiol 2001; 85: 104–12PubMedCrossRefGoogle Scholar
  10. 10.
    Baumgartner RN, Siervogel RM, Chumlea WC, et al. Associations between plasma lipoprotein cholesterols, adiposity and adipose tissue distribution during adolescence. Int J Obes 1989; 13: 31–41PubMedGoogle Scholar
  11. 11.
    Rowland TW. The physiological impact of intensive training on the prepubertal athlete. In: Cahill BR, Pearl AJ, editors. Intensive participation in children’s sports. Champaign (IL): Human Kinetics, 1993: 167–93Google Scholar
  12. 12.
    Hickman TB, Briefel RR, Carroll MD, et al. Distributions and trends of serum lipid levels among United States children and adolescents ages 4–19 years: data from the Third National Health and Nutrition Examination Survey. Prev Med 1998; 27: 879–90PubMedCrossRefGoogle Scholar
  13. 13.
    Eisenmann JC, Womack CJ, Reeves MJ, et al. Blood lipids in young distance runners. Med Sci Sports Exerc 2001; 33: 1161–9Google Scholar
  14. 14.
    Christenson B, Glueck C, Kwiterovich P, et al. Plasma cholesterol and triglyceride distributions in 13,665 children and adolescents: the Prevalence Study of the Lipid Research Clinics Program. Pediatr Res 1980; 14: 194–202CrossRefGoogle Scholar
  15. 15.
    Haskell WL. The influence of exercise on the concentrations of triglyceride and cholesterol in human plasma. Exerc Sport Sci Rev 1984; 12: 205–44PubMedCrossRefGoogle Scholar
  16. 16.
    Gutgessel HP, Atkins DL, Day RW. Common cardiovascular problems in the young. Part II: hypertension, hypercholesterolemia and preparticipation screening of athletes. AmFam Physician 1997; 56: 1993–8Google Scholar
  17. 17.
    National Cholesterol Education Program. Report of the expert panel on blood cholesterol levels in children and adolescents. Pediatrics 1992; 89 (3 Pt 2): 525–84Google Scholar
  18. 18.
    Freedman DS, Srinivasan SR, Harsha DW, et al. Relation of body fat patterning to lipid and lipoprotein concentrations in children and adolescents: the Bogolusa Heart Study. Am J Clin Nutr 1989; 50: 930–9PubMedGoogle Scholar
  19. 19.
    Tolfrey K, Campbell IG, Jones AM. Selected predictor variables and the lipid-lipoprotein profile of prepubertal girls and boys. Med Sci Sports Exerc 1999; 31: 1550–7PubMedCrossRefGoogle Scholar
  20. 20.
    Suter E, Hawes MR. Relationship of physical activity, body fat, diet, and blood lipid profile in youths 10–15 yr. Med Sci Sports Exerc 1993; 25: 748–54PubMedGoogle Scholar
  21. 21.
    Katzmarzyk PT, Malina RM. The contribution of participation in organized youth sports to daily energy expenditure in children and youth. East Lansing (MI): Institute for the Study of Youth Sports, 1997Google Scholar
  22. 22.
    Superko HR. Exercise training, serum lipids, and lipoprotein particle: is there a change threshold? Med Sci Sports Exerc 1991; 23: 677–85PubMedGoogle Scholar
  23. 23.
    Williams PT. Lipoproteins and adiposity show improvement at substantially higher exercise levels than those currently recommended [abstract]. Circulation 1994; 90: I471CrossRefGoogle Scholar
  24. 24.
    Williams PT. High-density lipoprotein cholesterol and other risk factors for coronary heart disease in female runners. N Engl J Med 1996; 334: 1298–303PubMedCrossRefGoogle Scholar
  25. 25.
    Williams PT. Relationship of distance run per week to coronary heart disease risk factors in 8283 male runners. Arch Intern Med 1997; 157: 191–8PubMedCrossRefGoogle Scholar
  26. 26.
    Armstrong N, Simons-Morton B. Physical activity and blood lipids in adolescents. Pediatr Exerc Sci 1994; 6: 381–405Google Scholar
  27. 27.
    Tolfrey K, Jones AM, Campbell IG. The effects of aerobic exercise training on the lipid-lipoprotein profile of children and adolescents. Sports Med 2000; 29: 99–112PubMedCrossRefGoogle Scholar
  28. 28.
    Smith BW, Metheny WP, Sparrow AW. Serum lipid and lipoprotein profiles in age-group runners. In: Weiss MR, Gould D, editors. Sport for children and youths. Champaign (IL): Human Kinetics, 1986: 269–73Google Scholar
  29. 29.
    Tikkanen HO, Harkonen M, Naveri H, et al. Relationship of skeletal muscle fiber type to serum high density lipoprotein cholesterol and apolipoprotein A-I levels. Atherosclerosis 1991; 90: 49–57PubMedCrossRefGoogle Scholar
  30. 30.
    Nikkila EA, TaskinenM-R, Rehunen S, et al. Lipoprotein lipase activity in adipose tissue and skeletal muscle of runners: relation to serum lipoproteins. Metabolism 1978; 27: 1661–71PubMedCrossRefGoogle Scholar
  31. 31.
    Stefanik ML, Wood PD. Physical activity, lipid and lipoprotein metabolism, and lipid transport. In: Bouchard C, Shephard RJ, Stephens T, editors. Physical activity, fitness, and health. Champaign (IL): Human Kinetics, 1994: 417–31Google Scholar
  32. 32.
    Despres J-P, Moorjani S, Lupien PJ, et al. Regional distribution of body fat, plasma lipoproteins, and cardiovascular disease. Atherosclerosis 1990; 10: 497–511Google Scholar
  33. 33.
    Malina RM, Koziel S, Bielicki T. Variation in subcutaneous adipose tissue distribution associated with age, sex, and maturation. Am J Hum Biol 1999; 11: 189–200PubMedCrossRefGoogle Scholar
  34. 34.
    van Lenthe FJ, van Mechelen W, Kemper HCG, et al. Association of a central pattern of body fat with blood pressure and lipoproteins from adolescence into adulthood. Am J Epidemiol 1998; 147: 686–93PubMedCrossRefGoogle Scholar
  35. 35.
    Laskarzewski PM, Morrison JA, Gutai J, et al. High and low density lipoprotein cholesterols in adolescent boys: relationships with endogenous testosterone, estradiol, and Quetelet index. Metabolism 1983; 32: 262–71PubMedCrossRefGoogle Scholar
  36. 36.
    Srinivasan SR, Sundaram GS, Williamson GD, et al. Serum lipoproteins and endogenous sex hormones in early life: observations in children with different lipoprotein profiles. Metabolism 1985; 34: 861–7PubMedCrossRefGoogle Scholar
  37. 37.
    Roemmich JN, Rogol AD. Hormonal changes during puberty and their relationship to fat distribution. Am J Hum Biol 1999; 11: 209–24PubMedCrossRefGoogle Scholar
  38. 38.
    Eisenmann JC, Malina RM. Age-related changes in subcutaneous adipose tissue of adolescent distance runners and association with blood lipoproteins. Ann Hum Biol. In pressGoogle Scholar
  39. 39.
    Malina RM, Bouchard C, Bar-Or O. Growth, maturation, and physical activity. 2nd ed. Champaign (IL): Human Kinetics. In pressGoogle Scholar
  40. 40.
    Malina RM, Bouchard C. Subcutaneous fat distribution during growth. In: Bouchard C, Johnston FE, editors. Fat distribution during growth and later health outcomes. New York: Wiley- Liss, 1988: 63–84Google Scholar
  41. 41.
    Durstine JL, Haskell WL. Effects of exercise training on plasma lipids and lipoproteins. Exerc Sport Sci Rev 1994; 22: 477–521PubMedGoogle Scholar
  42. 42.
    Leon AS, Rice T, Mandel S, et al. Blood lipid response to 20 weeks of supervised exercise in a large biracial population: the Heritage Family Study. Metabolism 2000; 49: 513–20PubMedCrossRefGoogle Scholar

Copyright information

© Adis International Limited 2002

Authors and Affiliations

  1. 1.Division of Kinesiology and Health, Pediatric Health and Performance LaboratoryUniversity of WyomingLaramieUSA

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