Sports Medicine

, Volume 31, Issue 15, pp 1025–1031 | Cite as

Estrogen Replacement Therapy and Female Athletes

Current Issues
  • David C. Cumming
  • Ceinwen E. Cumming
Leading Article


Physicians commonly recommend estrogen replacement as treatment for exercise-associated amenorrhoea. While the evidence shows that the basis of the amenorrhoea is estrogen deficiency, it is not clear that it is the only factor in the development of lowered bone density found in oligo-amenorrhoeic female athletes. Nutritional factors, significant in the development of the reproductive dysfunction, could also contribute to bone loss. No randomised, controlled studies of estrogen replacement in athletes have been published. However, one non-randomised study of a small group of athletes does suggest that there are significant gains in bone density to be made by the initiation of estrogen therapy. More research is clearly needed.


Bone Mineral Density Anorexia Nervosa Premature Ovarian Failure Cyproterone Acetate Hypothalamic Amenorrhoea 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The authors have no conflicts of interest.


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Copyright information

© Adis International Limited 2001

Authors and Affiliations

  1. 1.Department of Obstetrics and GynaecologyUniversity of Alberta, 201 Community Services Centre, Royal Alexandra HospitalEdmontonCanada

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