Drugs

, Volume 58, Supplement 2, pp 318–319 | Cite as

Trovafloxacin vs Ceftriaxone/Cefpodoxime ± Erythromycin in Hospitalised Community-Acquired Pneumonia

  • D. Williams Hopkins
  • R. Daniel
  • the Trovafloxacin Study Group
Poster Presentations Extended Abstract
  • 17 Downloads

References

  1. 1.
    Niederman MS, Bass JB, Campbell GD, et al. Guidelines for the initial management of adults with community-acquired pneumoniae: diagnosis, assessment of severity, and initial antimicrobial therapy. Am Rev Respir Dis 1993; 148: 1418–26PubMedGoogle Scholar
  2. 2.
    Brighty KE, Gootz TD. The chemistry and biological profile of trovafloxacin. J Antimicrob Chemother 1997; 39 Suppl. B: 1–14PubMedCrossRefGoogle Scholar
  3. 3.
    Teng R, Harris SC, Nix DE, et al. Pharmacokinetics and safety of trovafloxacin (CP-99,219), a new quinolone antibiotic, following administration of single oral doses to healthy male volunteers. J Antimicrob Chemother 1995; 36: 385–94PubMedCrossRefGoogle Scholar
  4. 4.
    Vincent J, Venitz J, Teng R, et al. Pharmacokinetics and safety of trovafloxacin in healthy male volunteers following administration of single intravenous doses of the prodrug, alatrofloxacin. J Antimicrob Chemother 1997; 39 Suppl. B: 75–80PubMedCrossRefGoogle Scholar
  5. 5.
    Andrews JM, Honeybourne D, Brenwald NP, et al. Concentrations of trovafloxacin in bronchial mucosa, epithelial lining fluid, alveolar macrophages and serum after administration of single or multiple oral doses to patients undergoing fibre-optic bronchoscopy. J Antimicrob Chemother 1997; 39: 797–802PubMedCrossRefGoogle Scholar
  6. 6.
    Vincent J, Dogolo J, Baris B A, et al. Single- and multiple-dose administration, dosing regimens, and pharmacokinetics of trovafloxacin and alatrofloxacin in man. Eur J Clin Microbiol Infect Dis 1998; 17: 427–30PubMedGoogle Scholar

Copyright information

© Adis International Limited 1999

Authors and Affiliations

  • D. Williams Hopkins
    • 1
  • R. Daniel
    • 2
  • the Trovafloxacin Study Group
  1. 1.Pfizer Central ResearchSandwichEngland
  2. 2.Pfizer Central ResearchSandwichEngland

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