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Drugs

, Volume 49, Supplement 2, pp 266–268 | Cite as

Antimicrobial Evaluation of Nadifloxacin (OPC-7251), a New Topical Quinolone, in Acne Vulgaris

  • Konstanze Vogt
  • H. Hahn
  • J. Hermann
  • U. F. Haustein
  • U. Blume
  • H. Gollnick
  • C. E. Orfanos
In Vitro and In Vivo Antibacterial Activity

Keywords

Minimum Inhibitory Concentration Adis International Limited Acne Minimum Inhibitory Concen Fusidic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Leeming JP, Holland KT, Cuniffe WJ. The microbial colonization of inflamed acne vulgaris lesions. Br J Dermatol 1988; 118: 203–8PubMedCrossRefGoogle Scholar
  2. 2.
    Eady EA, Cove JH, Holland KT, et al. Erythromycin resistant propionibacteria in antibiotic treated acne patients: association with therapeutic failure. Br J Dermatol 1989; 121: 51–7PubMedCrossRefGoogle Scholar
  3. 3.
    Kawabata S, Ohguro K, Mukai F, et al. Bacteriological evaluation of OPC-7251, a new pyridone caboxylic acid antimicrobial agent. I. In vitro antibacterial activity. Jpn J Chemother 1989; 37: 1160–78Google Scholar
  4. 4.
    Kawabata S, Masada H, Wakebe H, et al. Bacteriological evaluation of OPC-7251, a new pyridone carboxylic acid antimicrobial agent. II. Therapeutic effect of OPC-7251 cream on experimental infection model in mice. Jpn J Chemother 1989; 37: 1179–83Google Scholar
  5. 5.
    Eady EA, Ross JI, Cove JH, et al. The effects of oral erythromycin therapy for acne on the development of resistance in cutaneous staphylococci and propionibacteria In: Marks R, Plewig G, editors. Acne and related disorders. London: Martin Dunitz, 1989: 265–70Google Scholar

Copyright information

© Adis International Limited 1995

Authors and Affiliations

  • Konstanze Vogt
    • 1
  • H. Hahn
    • 1
  • J. Hermann
    • 2
  • U. F. Haustein
    • 2
  • U. Blume
    • 3
  • H. Gollnick
    • 3
  • C. E. Orfanos
    • 3
  1. 1.Department of MicrobiologyRudolf Virchow University HospitalBerlinGermany
  2. 2.Department of DermatologyUniversity of LeipzigLeipzigGermany
  3. 3.Department of DermatologyUniversity Medical Centre Steglitz, Free University of BerlinBerlinGermany

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