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Drugs

, Volume 44, Issue 5, pp 720–727 | Cite as

Use of Plasma Volume Expanders in Myocardial Revascularisation

  • John H. Lacy
  • Creighton B. Wright
Practical Therapeutics

Summary

The optimal solution for priming cardiopulmonary bypass machines and for postoperative resuscitation following myocardial revascularisation should be inexpensive, free of risk of transmitting disease, and free of other detrimental side effects. Colloid solutions are preferred over crystalloid solutions because of elevations in extracellular sodium and water that occur with cardiopulmonary bypass.

Albumin, plasma protein solution, hetastarch (hydroxyethyl starch) and dextran are available for use if blood is not necessary and mediastinal blood is not available. Hetastarch is associated with a lower risk of bleeding and less risk of allergic reaction than dextran, and its cost is substantially less than that of albumin. However, high doses increase the risk of bleeding complications.

Keywords

Dextran Cardiopulmonary Bypass Hydroxyethyl Starch Myocardial Revascularisation Colloid Osmotic Pressure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Adis International Limited 1992

Authors and Affiliations

  • John H. Lacy
    • 1
  • Creighton B. Wright
    • 1
  1. 1.Department of SurgeryThe Jewish Hospital of CincinnatiCincinnatiUSA

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