Advertisement

Drugs

, Volume 43, Issue 4, pp 440–442 | Cite as

Cyclosporin for Crohn’s Disease?

  • Mario Guslandi
  • A. Tittobello
Leading Article

Keywords

Cyclosporin Flumazenil Logy Unit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Allison MC, Pounder RE. Cyclosporin for Crohns’ disease. Alimentary Pharmacology and Therapeutics 1: 39–43, 1987PubMedCrossRefGoogle Scholar
  2. Ardizzone S, Fasoli R, Sangaletti O, Petrillo M, Bianchi Porro G. The treatment of chronically active Crohn’s disease with cyclosporin A. Current Therapeutic Research 48: 1–4, 1980Google Scholar
  3. Baker K, Jewell DP. Cyclosporin for the treatment of severe inflammatory bowel disease. Alimentary Pharmacology and Therapeutics 3: 143–149, 1989PubMedCrossRefGoogle Scholar
  4. Brynskov J, Freund L, Rasmussen SN, Lauritsen K, de Muckadell OS, et al. A placebo-controlled, double-blind randomized trial of cyclosporine therapy in active chronic Crohn’s disease. New England Journal of Medicine 321: 845–850, 1989PubMedCrossRefGoogle Scholar
  5. Brynskov J, Freund L, Rasmussen SN, Lauritsen K, de Muckadell OS, et al. Final report on a placebo-controlled, double-blind, randomized, multicentre trial of cyclosporin treatment in active chronic Crohn’s disease. Scandinavian Journal of Gastroenterology 26: 689–695, 1991PubMedCrossRefGoogle Scholar
  6. Brynskov J, Thomsen H, Nielsen SL. Renographic monitoring of renal function in patients with Crohn’s disease treated with low dose cyclosporin: a controlled study. British Medical Journal 300: 1438–1439, 1990PubMedCrossRefGoogle Scholar
  7. Fukushima T, Sugita A, Masuzawa S, Yamazaki Y, Tsuchiya S. Effects of cyclosporin A on Crohn’s active disease. Gastroen-terologia Japonica 24: 12–15, 1989Google Scholar
  8. Harris DT, Kozumbo WJ, Cerutti PA, Cerottini JC. Mechanisms of cyclosporin A-induced immunosuppression. Cellular Immunology 109: 104–114, 1987PubMedCrossRefGoogle Scholar
  9. Lobo AJ, Juby LD, Axon ATR. Cyclosporine in Crohn’s disease. New England Journal of Medicine 322: 636, 1990CrossRefGoogle Scholar
  10. Lobo AJ, Juby LD, Rothwell J, Poole TW, Axon ATR. Long-term treatment of Crohn’s disease with cyclosporine: the effect of a very low dose on maintenance of remission. Journal of Clinical Gastroenterology 13: 42–45, 1991PubMedCrossRefGoogle Scholar
  11. Lofberg R, Angelin B, Einarsson K, Gabrielsson N, Ost L. Unsatisfactory effect of cyclosporin A treatment in Crohn’s disease: a report of five cases. Journal of Internal Medicine 226: 157–161, 1989PubMedCrossRefGoogle Scholar
  12. Mitchell IC, Turk JL. Effect of the immunemodulating agents cyclophosphamide, methotrexate, hydrocortisone and cyclosporin A on an animal model of granulomatous bowel disease. Gut 31: 674–678, 1990PubMedCrossRefGoogle Scholar
  13. Parrott NR, Taylor RMR, Venables CW, Record OC. Treatment of Crohn’s disease in relapse with cyclosporin A. British Journal of Surgery 75: 1185–1188, 1988PubMedCrossRefGoogle Scholar
  14. Peltekian KM, Williams CN, MacDonald AS, Roy PD, Czolpinska E. Open trial of cyclosporine in patients with severe active Crohn’s disease refractory to conventional therapy. Canadian Journal of Gastroenterology 2: 5–11, 1988Google Scholar
  15. Ranzi T, Campanini MC, Quarto di Palo F, Velio P, Bianchi PA. Cyclosporin A in Crohn’s disease. Current Therapeutic Research 45: 245–252, 1989Google Scholar
  16. Sachar DB. Cyclosporin in Crohn’s disease. New England Journal of Medicine 322: 637, 1990CrossRefGoogle Scholar
  17. Stange EF, Fleig WE, Rehklau E, Ditschuneit H. Cyclosporin A treatment in inflammatory bowel disease. Digestive Diseases and Sciences 34: 1387–1392, 1989PubMedCrossRefGoogle Scholar
  18. Summers RW, Switz DM, Sessions Jr JT, Becktel JM, Best WR, et al. National cooperative Crohn’s disease study: results of drug treatment. Gastroenterology 77: 847–869, 1979PubMedGoogle Scholar
  19. Thomson AW, Neild GH. Cyclosporin: use outside transplantation. British Journal 302: 4–5, 1991CrossRefGoogle Scholar

Copyright information

© Adis International Limited 1992

Authors and Affiliations

  • Mario Guslandi
    • 1
  • A. Tittobello
    • 1
  1. 1.Gastroenterology Unit, S. Raffaele HospitalUniversity of MilanMilanItaly

Personalised recommendations