Efficacy and Tolerability of Cefixime in Otitis Media
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A large scale multicentre clinical study was undertaken to assess the efficacy and tolerability of cefixime in the treatment of acute otitis media in children. A total of 25 863 evaluable children with acute otitis media received cefixime 8 mg/kg once daily for at least 10 days.
At the end of treatment, 86% of patients were considered to be either cured or improved. These results are consistent with those achieved with cefixime in controlled clinical trials. Adverse effects were reported in 11.5% of patients, but were judged to be related to cefixime therapy in only 9.4% of patients.
The results of this study demonstrate that cefixime is an effective and well tolerated treatment for acute otitis media in children.
KeywordsOtitis Medium Acute Otitis Medium Cefixime Amox Large Scale Clinical Study
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