, Volume 39, Issue 3, pp 394–398 | Cite as

Self-Administration in the Pharmacological Treatment of Impotence

  • Francois Bénard
  • Tom F. Lue
Practical Therapeutic


Recent innovative research into the physiology and pharmacology of erection and the introduction of intracavernous injection of vasoactive agents have revolutionised our approach to the diagnosis and treatment of impotence. A thorough understanding of the rationale, indications, precautions and potential complications of intracavernous self-injection is essential for successful management.

The commonly used drugs for injection are papaverine, either alone or in combination with phentolamine, and alprostadil (prostaglandin E1). The major adverse effects include priapism, prolonged erection, and fibrosis of the erectile tissue. With the proper technique and appropriate dosage, this is a safe, minimally invasive, and highly effective treatment.


Impotence Papaverine Phentolamine Priapism Alprostadil 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© ADIS Press Limited 1990

Authors and Affiliations

  • Francois Bénard
    • 1
  • Tom F. Lue
    • 1
  1. 1.Department of Urology, U-518University of California School of MedicineSan FranciscoUSA

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