The Place of Temocillin in the Treatment of Hospital Infections
- 6 Downloads
Infection due to Gram-negative bacteria continues to be a common problem in the hospital environment, for which a wide variety of antibiotics is available. Among Enterobacteria, resistance is expressed most commonly via β-lactamases. Temocillin is the first penicillin to show stability to β-lactamases of Gram-negative bacteria, therefore it is in this type of infection that the initial assessments of temocillin should be made.
KeywordsPiperacillin Carbenicillin Cefoperazone Temocillin Hospital Infection
Unable to display preview. Download preview PDF.
- Slocombe, B.; Basker, M.J.; Bentley, P.H.; Clayton, J.P.; Cole, M.; Comber, K.R.; Dixon, R.A.; Edmondson, R.A.; Jackson, D.; Mierrikin, D.J. and Sutherland, R.: BRL 17421, a novel beta-lactam antibiotic, highly resistant to beta-lactamases, giving high and prolonged serum levels in humans. Antimicrobial Agents and Chemotherapy 20: 38–46 (1981).PubMedCrossRefGoogle Scholar
- Whitaker, S.; Hajipieris, P. and Williams, J.D.: Distribution and type of beta-lactamase amongst 1,000 Gram-negative rod bacteria; in Spitzy et al. (Eds) Proceedings of the 13th International Congress of Chemotherapy, Vienna, Austria, 1983.Google Scholar