Drugs

, Volume 29, Supplement 5, pp 191–193 | Cite as

Temocillin in the Treatment of Serious Gram-Negative Infections

  • Gavin Lindsay
  • Alistair D. Beattie
  • Eric W. Taylor
Section 4: Temocillin in Severe Hospital Infections

Summary

Temocillin was used to treat 32 patients with proven or suspected infection caused by aerobic Gram-negative bacteria. 25 of these patients were assessable on clinical and bacteriological grounds. All 25 were either cured or improved, although in 5 patients with urinary tract infection there was relapse of infection or reinfection following the cessation of therapy. Clinical improvement was usually rapid and no serious side effect was noted.

Temocillin would thus appear to be an effective and safe agent for the treatment of bacterial infection caused by aerobic Gram-negative organisms.

Keywords

Urinary Tract Infection Temocillin Flucloxacillin Ischaemic Gangrene Infected Aortic Graft 

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Reference

  1. Slocombe, B.; Basker, M.J.; Bentley, P.H.; Clayton, J.P.; Cole, M. et al.: BRL 17421, a novel β-lactam antibiotic, highly resistant to β-lactamases giving high and prolonged serum levels in humans. Antimicrobial Agents and Chemotherapy 20: 38–46 (1981).PubMedCrossRefGoogle Scholar

Copyright information

© ADIS Press Limited 1985

Authors and Affiliations

  • Gavin Lindsay
    • 1
  • Alistair D. Beattie
    • 1
  • Eric W. Taylor
    • 2
  1. 1.Department of BacteriologySouthern General HospitalGlasgowScotland
  2. 2.Vale of Leven HospitalAlexandriaUK

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