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Drugs

, Volume 29, Supplement 5, pp 151–153 | Cite as

Lung Tissue Penetration of Temocillin

  • W. Cowan
  • A. Baird
  • J. D. Sleigh
  • J. M. B. Gray
  • J. M. Leiper
  • D. H. Lawson
Section 2: The Clinical Pharmacology of Temocillin

Summary

Eight patients about to have the whole or part of a lung resected were given a 2g bolus dose of temocillin. A series of serum samples and a piece of peripheral lung tissue were collected and assayed for temocillin concentration. 30 minutes after drug administration, the mean serum and tissue concentrations were 172 mg/L and 45 mg/kg respectively.

Keywords

Lung Tissue Tissue Concentration Antimicrobial Chemotherapy Temocillin Respiratory Tract Infec 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© ADIS Press Limited 1985

Authors and Affiliations

  • W. Cowan
    • 1
  • A. Baird
    • 1
  • J. D. Sleigh
    • 1
  • J. M. B. Gray
    • 1
  • J. M. Leiper
    • 1
  • D. H. Lawson
    • 1
  1. 1.Departments of Bacteriology and Clinical PharmacologyGlasgow Royal InfirmaryGlasgowScotland

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