Drugs

, Volume 29, Supplement 5, pp 151–153 | Cite as

Lung Tissue Penetration of Temocillin

  • W. Cowan
  • A. Baird
  • J. D. Sleigh
  • J. M. B. Gray
  • J. M. Leiper
  • D. H. Lawson
Section 2: The Clinical Pharmacology of Temocillin

Summary

Eight patients about to have the whole or part of a lung resected were given a 2g bolus dose of temocillin. A series of serum samples and a piece of peripheral lung tissue were collected and assayed for temocillin concentration. 30 minutes after drug administration, the mean serum and tissue concentrations were 172 mg/L and 45 mg/kg respectively.

Keywords

Lung Tissue Tissue Concentration Antimicrobial Chemotherapy Temocillin Respiratory Tract Infec 

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References

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Copyright information

© ADIS Press Limited 1985

Authors and Affiliations

  • W. Cowan
    • 1
  • A. Baird
    • 1
  • J. D. Sleigh
    • 1
  • J. M. B. Gray
    • 1
  • J. M. Leiper
    • 1
  • D. H. Lawson
    • 1
  1. 1.Departments of Bacteriology and Clinical PharmacologyGlasgow Royal InfirmaryGlasgowScotland

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